康妇消炎栓与盐酸左氧氟沙星治疗盆腔炎患者的临床疗效

谢珺

【摘要】目的：以盆腔炎患者为研究对象，观察其临床用药情况，分析不同治疗的的临床疗效。方法：研究起始时间为2020年3月，停止时间为2023年5月，纳入此间盆腔炎患者共计120例，以此展开研究分析。遵从随机数字表法平均分组，各自含有60例患者。对照组使用单一药物治疗，联用组使用本文研究的联合药物治疗，均同意持续用药治疗2周。记录两组患者盆腔积液消失时间、白带分泌恢复正常时间、下腹坠痛消失时间，比较治疗前后两组患者白细胞介素-6（IL-6）、C反应蛋白（CRP）和肿瘤坏死因子-a（TNF-a）水平，评估两组患者临床治疗效果，同时比较两组不良反应的发生情况。结果：治疗后，联用组患者的盆腔积液消失时间、白带分泌恢复正常时间、下腹坠痛消失时间均比对照组短（P<0.05），且IL-2、CRP、TNF-a水平均低于对照组（P<0.05）。联用组总有效率为91.66%，比对照组78.33%高（P<0.05），联用组和对照组患者不良反应发生率分别为10.00%和11.67%，其对比差异无统计学意义（P>0.05）。结论 对盆腔炎患者采用研究药物联合治疗的疗效较确切，能够快速缓解患者临床症状，减少体内炎性因子数量，安全性良好，值得在临床上推广运用。

【關键词】盐酸左氧氟沙星；康妇消炎栓；盆腔炎

Clinical effect of kangfu xiaoyan supposant and levofloxacin hydrochloride on patients with pelvic inflammatory disease

XIE Jun

Gangu County Peoples Hospital， Tianshui City， Gansu Province， Tianshui， Gansu 741200， China

【Abstract】Objective：To observe the clinical medication status of patients with pelvic inflammatory disease and analyze the clinical efficacy of different treatments.Methods： The method study started in March 2020 and stopped in May 2023. A total of 120 patients with pelvic inflammatory disease were included in this study for analysis. Follow the random number table method to group evenly， each containing 60 patients. The control group was treated with a single medication， while the combination group was treated with the combination medication studied in this study. Both agreed to continue medication for 2 weeks. Record the disappearance time of pelvic fluid accumulation， recovery time of vaginal discharge， and disappearance time of lower abdominal pain in two groups of patients. Compare the levels of interleukin-6 （IL-6）， C-reactive protein （CRP）， and tumor necrosis factor-a （TNF-a） before and after treatment， evaluate the clinical treatment effect of the two groups of patients， and compare the occurrence of adverse reactions between the two groups.Results： After treatment， the disappearance time of pelvic fluid accumulation， recovery time of vaginal discharge， and disappearance time of lower abdominal pain in the combination group were shorter than those in the control group （P<0.05）， and the levels of IL-2， CRP， and TNF-a were lower than those in the control group （P<0.05）. The total effective rate of the combination group was 91.66%， which was higher than 78.33% of the control group （P<0.05）. The incidence of adverse reactions in the combination group and the control group were 10.00% and 11.67%， respectively， with no statistically significant difference （P>0.05）. Conclusion： The combination therapy with investigational drugs has a definite therapeutic effect on patients with pelvic inflammatory disease， can quickly alleviate clinical symptoms， reduce the number of inflammatory factors in the body， and has good safety. It is worth promoting and applying in clinical practice.

【Key Words】Levofloxacin hydrochloride； Kang Fu anti-inflammatory suppository； Pelvic inflammatory disease

盆腔炎是一种女性常见的生殖道感染性疾病，下腹坠痛、盆腔滞留积液、白带分泌增多为该病主要临床症状。其是由于阴道或宫颈菌群感染引起的，如需氧菌、厌氧菌，好发于育龄期或初次性交年龄小、性生活频繁、性卫生不良的女性身上[1]。因其发病时间较长，病情较顽固，长时间得不到控制，病情加重可导致月经失调、异位妊娠 、不孕症，对妇女的身心健康造成严重不良影响[2]。因此，为避免盆腔炎患者病情进一步恶化，早发现早治疗显得尤为重要。……