中医辨证对消化性溃疡合并幽门螺杆菌感染治疗效果及清除率分析

魏红刚 白丽娜

【摘要】目的：中醫辨证对消化性溃疡合并幽门螺杆菌感染治疗效果及清除率分析。方法：研究对象具体构成为：我院诊治的消化性溃疡合并幽门螺杆菌感染患者，根据需要分组后，组别为：对照组、实验组，指导依据为：电脑随机法，且两组消化性溃疡合并幽门螺杆菌感染患者总例数为78；其中，39例在对照组中收入，39例在实验组中收入，两组入院时间开始于2021年3月，结束于2023年3月，在治疗阶段，将西医治疗为对照组提供，中医辨证治疗为实验组提供，就两组消化性溃疡合并幽门螺杆菌感染患者最终疗效展开比较。结果：两组患者治疗后幽门螺杆菌清除率和复发率比较，实验组幽门螺杆菌清除率高于对照组，实验组疾病复发率低于对照组（P<0.05）；两组患者治疗前血清肿瘤坏死因子、白细胞介素-6和胃泌素水平比较，没有显著差异，治疗后，实验组各项指标均低于对照组（P<0.05）；患者生存质量改善程度比较，治疗前，没有显著差异，治疗后，实验组各项评分均高于对照组（P<0.05）；并发症情况比较，实验组低于对照组（P<0.05）。结论：消化性溃疡合并幽门螺杆菌感染患者实施治疗期间，应用中医辨证治疗方案，对于患者治疗有效性优化显著，提升幽门螺杆菌清除率，避免疾病反复发作。

【关键词】消化性溃疡；幽门螺杆菌感染；中医辨证；治疗效果；清除率

Analysis of the therapeutic effect and clearance rate of peptic ulcer combined with Helicobacter pylori infection by Chinese medicine identification

WEI Honggang， BAI Lina

Fufeng County Peoples Hospital， Baoji， Shaanxi 722200， China

【Abstract】Objective： To analyze the therapeutic effect and clearance rate of H. pylori infection combined with peptic ulcer by Chinese medicine identification. Methods： The specific composition of the study population was： patients with peptic ulcer combined with H. pylori infection treated in our hospital， after grouping according to need， the groups were： control group， experimental group， guided by： computerized randomization method， and the total number of patients with peptic ulcer combined with H. pylori infection in the 2 groups was 78； among them， 39 cases were admitted in the control group and 39 cases were admitted in the experimental group， The admission of the 2 groups began in March 2021 and ended in March 2023， and during the treatment phase， Western medical treatment was provided for the control group and Chinese medical identification treatment was provided for the experimental group to compare the final efficacy of the 2 groups of patients with peptic ulcer combined with H. pylori infection. Results： Comparison of H. pylori clearance rate and recurrence rate after treatment between the two groups， the clearance rate of H. pylori in the experimental group was higher than that in the control group， and the recurrence rate of disease in the experimental group was lower than that in the control group（P<0.05）； There was no significant difference in serum tumor necrosis factor， interleukin-6 and gastrin levels between the two groups before treatment， and after treatment， all indexes in the experimental group were lower than those in the control group（P<0.05）； There was no significant difference in the degree of improvement of patients quality of survival before treatment， and after treatment， all scores in the experimental group were higher than those in the control group（P<0.05）； the complications were lower in the experimental group than in the control group（P<0.05）. Conclusion： During the implementation of treatment for patients with peptic ulcer combined with Helicobacter pylori infection， the application of Chinese medicine identification treatment protocols optimizes the effectiveness of treatment for patients significantly， improves the clearance rate of Helicobacter pylori， and avoids recurrent attacks of the disease.

【Key Words】Peptic ulcer； Helicobacter pylori infection； Chinese medicine identification； Therapeutic effect； Clearance rate

消化系统疾病中常见消化性溃疡，发病率较高，幽门螺旋菌导致消化系统疾病的主要致病因素，是病菌感染导致的慢性胃炎[1]。消化性溃疡合并幽门螺杆菌感染患者临床多采取抗生素开展治疗，但是实施治疗过程中应用的抗生素容易造成治疗效果不佳，产生耐药性[2]。为了确保为患者实施药物治疗的有效性，需要对药物治疗方案进行优化，从中医辨证治疗的角度，本文将探究为患者实施中医药物治疗方案的效果[3]。

1 资料与方法

1.1 一般资料

实验时间区间2021年3月—2023年3月，实验样本：78例消化性溃疡合并幽门螺杆菌感染患者，电脑随机法将患者划分为实验组和对照组，将西医治疗为对照组提供，中医辨证治疗为实验组提供。……