锌制剂口服联合蒙脱石散保留灌肠辅助治疗小儿腹泻的临床效果

张永英　陈君玲

[摘要] 目的 探讨锌制剂口服联合蒙脱石散保留灌肠辅助治疗小儿腹泻的临床效果。 方法 将2013年2～12月本院收治的120例小儿腹泻患儿，随机分为观察组和对照组，对照组60例患儿给予补液、纠正酸碱平衡、抗感染等对症治疗，观察组60例患儿在上述治疗的基础上给予锌制剂口服、蒙脱石散保留灌肠辅助治疗，观察两组患者的治疗效果及腹泻控制情况。 结果 治疗后观察组显效率和总有效率均明显高于对照组，差异有统计学意义（P<0.05）；观察组患者腹泻控制时间明显短于对照组，差异有统计学意义（P<0.05）。 结论 锌制剂口服联合蒙脱石散保留灌肠辅助治疗小儿腹泻的效果较好，腹泻控制时间短，值得应用。

[关键词] 小儿腹泻；锌制剂；蒙脱石散；保留灌肠；临床效果

[中图分类号] R725.7 [文献标识码] A [文章编号] 1674-4721（2014）04（b）-0066-03

[Abstract] Objective To investigate the clinical effect of oral zinc preparations， montmorillonite powder retention enema adjuvant therapy in infantile diarrhea enema. Methods 120 cases of pediatric diarrhea in our hospital from February 2013 to December 2013 were randomly divided into observation group and control group，the 60 patients in control group were given fluid infusion，correcting acid-base balance，antibiotics treatment and other symptomatic treatment，60 patients in observation group were given zinc preparations oral，montmorillonite powder retention enema adjuvant therapy on the basis of control group，therapeutic effects and diarrhea control situation of two groups were observed. Results After treatment，the efficiency rate and the total effective rate of observation group were significantly higher than those of control group，the difference was statistically significant （P<0.05），the diarrhea control time of observation group was significantly shorter than that of control group，the difference was statistically significant （P<0.05）. Conclusion The clinical effect of zinc preparations oral，montmorillonite powder retention enema adjuvant therapy in infantile diarrhea enema is good，diarrhea control time is short，it is worthy of application.

[Key words] Pediatric diarrhea；Zinc preparations；Montmorillonite powder；Retention enema；Clinical effects

小儿腹泻是由多种因素引起的以腹泻、呕吐为主要症状的胃肠道功能紊乱综合征，是儿科常见病，多发于2岁以下婴幼儿，若不及时治疗可导致严重水电解质紊乱，甚至危及生命，对儿童的生长发育和健康造成严重影响[1]。目前临床尚无根治方法，常规处理方法为补液控制感染等，有研究显示，在常规治疗的基础上给予灌肠、胃肠保护剂等辅助治疗，可有效改善患儿的肠功能，减少细菌毒素吸收[2]。本研究选择本院收治的小儿腹泻患儿，给予锌制剂口服联合蒙脱石散灌肠辅助治疗，以探讨其治疗效果。

1 资料与方法

1.1 一般资料

选择2013年2～12月本院收治的120例小儿腹泻患儿为研究对象，均符合1998年中国腹泻病诊断治疗方案中的小儿腹泻诊断标准[3]，入院前未采用其他治疗措施，入院后进行详细的体格检查，排除免疫性、遗传性、血液病等其他原因，排除对相应治疗药物过敏者。……