谢若欣 梁晓红 霍乐颍


[摘要] 目的 探讨日光照射对新生儿黄疸早期干预的临床疗效。 方法 将本院爱婴区2013年2~5月收治的216例足月分娩的新生儿随机分为观察组与对照组。对照组采用口服小剂量苯巴比妥促进肝酶活性;观察组在对照组基础上加用裸体日光照射。记录两组干预后第0、24、48、72 h的经皮测胆红素值,并比较两组新生儿的转科率。 结果 干预后观察组经皮测胆红素值低于对照组(P<0.05),观察组符合高胆红素血症标准且需转新生儿科占0.93%,对照组占6.48%,两组差异有统计学意义(P<0.05)。 结论 日光照射干预新生儿黄疸的疗效明显、简便易行、经济实惠,可推广应用。
[关键词] 日光照射;新生儿黄疸;早期干预
[中图分类号] R722.17 [文献标识码] A [文章编号] 1674-4721(2015)06(c)-0038-03
[Abstract] Objective To explore the clinical curative effect of solar radiation for neonatal jaundice early intervention. Methods 216 newborns of full term delivery admitted into our hospital baby care from February to May 2013 were divided into observation group and control group.Oral low-dose phenobarbital was given to the control group to promote enzyme activity of liver.On the basis of control group,naked solar radiation was added to observation group.At 0th,24th,48th and 72th hour after intervention,percutaneous bilirubin measurement values between two groups was recorded,the transfer rate of newborn was compared. Results After the intervention,percutaneous bilirubin measurement values in observation group was lower than that of control group(P<0.05).The proportion of newborns who met the hyperbilirubinemia criteria that needed to transfer into neonatal department in observation group was 0.93%,in control group was 6.48%,the difference was significant(P<0.05). Conclusion The effect of solar radiation intervention on neonatal jaundice is remarkable,and it is simple and affordable,which is worthy of clinical promotion and application.
[Key words] Solar radiation;Neonatal jaundice;Early intervention
新生儿黄疸是儿科最常见的症状之一,是指出生28 d内的新生儿由于胆红素代谢异常,致使血中胆红素水平升高,表现为皮肤、黏膜及巩膜黄疸为特征的病症[1]。一般新生儿生后2~3 d出现黄疸,4~5 d达高峰,5~7 d消退,最迟不超过2周,早产儿可延迟到3~4周。黄疸有生理性和病理性之分;病理性黄疸相对生理性黄疸而言是血清胆红素水平异常增高或胆红素增高性质的改变,某些增高是属于生理性黄疸的延续或加深[2];病理性黄疸对新生儿的身体影响较大,尤其是对新生儿的脑组织会造成严重损伤[3],导致胆红素脑病。日本曾报道,高胆发病率占新生儿住院病例的首位[4]。因此,在爱婴区需积极干预黄疸以减少母婴分离,其中日光照射是一种简便易行、经济实惠的方法。本研究探讨日光照射对新生儿黄疸早期干预的临床疗效。
1 资料与方法
1.1 一般资料
选择2013年2~5月在本院产科爱婴区出生的216例足月新生儿作为研究对象,其均符合以下条件:①除黄疸外无其他异常情况,排除合并感染、出生窒息、家族存在G6PD缺乏症、母亲产前血清抗ABO抗体阳性者;……