同步放化疗对进展期肺癌患者癌因性疲乏及心理护理需求指标的影响

黄琼英　卓妍　吴秀华

[摘要] 目的 探讨同步放化疗对进展期肺癌患者癌因性疲乏及心理护理需求指标的影响。 方法 选取2012年2月～2013年2月在我院就诊晚期肺癌患者85例，随机分组法分为观察组43例及对照组42例。观察其对癌因性疲乏及心理护理需求指标的影响。 结果 观察组FACT-G总分显著高于对照组，两组比较，差异有统计学意义（P<0.05）。观察组生理维度、社会/家庭维度、情感维度、功能维度各指标得分均高于对照组，差异有统计学意义（P<0.05）。两组干预前后生活质量和功能状况各项得分比较，差异有统计学意义（P<0.05）；两组各项指标干预后各项得分比较，观察组显著高于对照组，差异有统计学意义（P<0.05）。观察组患者干预后综合疲劳程度、综合疲劳影响及SRSS得分显著下降，与干预前比较，差异有统计学意义（P<0.05）；干预后观察组患者与对照组比较，差异有统计学意义（P<0.05）；观察组患者的心理护理需求指标，包括心理护理总时间，每天心理护理心理护理总频次时间，每天心理护理频次皆高于对照组，两组比较差异有统计学意义（P<0.05）。 结论 同步放化疗可明确影响到进展期肺癌患者癌因性疲乏评分，心理护理需求增加。

[关键词] 同步放化疗；进展期肺癌；癌因性疲乏；心理护理需求

[中图分类号] R734.2 [文献标识码] B [文章编号] 2095-0616（2016）01-117-04

[Abstract] Objective To study the effect of concurrent chemotherapy and radiotherapy on cancer-related fatigue and demand parameter of psychological nursing in patients with lung cancer in progressive stage. Methods 85 patients with advanced lung cancer， who were received and treated in our hospital from February 2012 to February 2013，were randomly selected and divided into observation group （43 cases） and control group （42 cases）.To observe the effect of concurrent chemotherapy and radiotherapy on cancer-related fatigue and demand parameter of psychological nursing. Results The total score of FACT-G，the various index score of biological dimensions，society or family dimensions， affective dimensions，functional dimensions in observation group were significantly higher than which in control group，the differences were statically significant（P<0.05）.The various score of life quality and functional status pre and post intervention were statically significant compared with the two groups（P<0.05），and which after intervention in observation group was obviously higher than which in control group， the differences was statically significant（P<0.05）.The compositive fatigue degree， the compositive fatigue influence， and SRSS score in observation group after intervention has significantly reduced compared with which before intervention， the differences was statically significant（P<0.05），and the differences of which after intervention was statically significant compared with the two groups（P<0.05）.The demand parameters of psychological nursing， the total time of psychological nursing， the total frequency time and frequency of psychological nursing in every day in observation group were higher than which in control group， the differences were statically significant（P<0.05）. Conclusion Concurrent chemotherapy and radiotherapy could affirmatory affect the cancer-related fatigue score of patients with lung cancer in progressive stage， could increase the demand of psychological nursing.

[Key words] Concurrent chemotherapy and radiotherapy；Lung cancer in progressive stage；Cancer-related fatigue；Demand of psychological nursing

肺癌是世界上人类恶性肿瘤的最常见的死因。癌因性疲劳是一种在癌症患者常见的主观症状之一，是由癌症引起或是癌症治疗的结果，是与活动无关的过度的全身不适反应，此症状持续时间长，且不会通过休息和睡眠得到缓解[1-2]。美国国家综合癌症网络将癌因性疲乏（cancer related fa-tigue，CRF）定义为一种扰乱机体正常功能的、非同寻常的、持久的、主观的劳累感，与癌症本身病理生理或癌症治疗有关。与一般劳累感不同，CRF发展快、程度重、能量消耗大、持续时间长（一般≥6个月），并且通常不能通过休息和睡眠来缓解[3]。本研究探讨同步放化疗对进展期肺癌患者癌因性疲乏及心理护理需求指标的影响，现报道如下。

1 资料与方法

1.1 一般资料

选取2012年2月～2013年2月在我院就诊进展期肺癌患者85例，其中男45例，女40例，年龄47～82岁，平均（57.5±11.1）岁。按照随机分组法分为观察组43例及对照组42例。观察组男23例，女20例，年龄47～79岁，平均（53.3±8.3）岁；对照组男22例，女20例，年龄51～82岁，平均（56.4±7.9）岁。两组患者皆知情同意，并自愿参加本研究。……