探讨胚胎发育不良性神经上皮肿瘤的MRI特征表现

苏怀盈　杨子江　吴凯明

【摘要】 目的：探讨胚胎发育不良性神经上皮肿瘤（DNET）MRI特征表现。方法：回顾分析7例经手术证实为DNET的MRI资料，总结DNET的MRI特征表现。结果：7例患者的肿瘤均在皮层或以皮层为主，病灶呈三角型，假囊肿样，T1WI呈低信号，T2WI呈高信号，T2 Flair呈低信号，病灶内分隔及周边呈高信号，DWI呈偏低信号，ADC值增高，增强扫描病灶内可见血管影穿行其中，病灶内见结节状强化及分隔强化或病灶无强化，边界欠清，无明显占位效应，瘤周未见水肿，伴周围脑皮质发育不良表现，临近颅骨呈受压改变。结论：胚胎发育不良性神经上皮肿瘤在MRI上具有特征性，提高对此病诊断率，对患者临床预后有较大的意义。

【关键词】 神经元肿瘤； 混合神经元肿瘤； 磁共振成像

中图分类号 R445.2 文献标识码 B 文章编号 1674-6805（2016）6-0059-02

The Specific MRI Features of Dysembryoplastic Neuroepithelial Tumor/SU Huai-ying，YANG Zi-jiang，WU Kai-ming.//Chinese and Foreign Medical Research，2016，14（6）：59-60

【Abstract】 Objective：To explore the specific MRI features of dysembryoplastic neuroepithelial tumor.Method：MRI of DNET confirmed by surgery and pathology in 7 cases were respectively analysed and MRI specific findings of DNET were summarized.Result：DNET in these 7 cases were within or mainly in cortex.They had triangular shape with pseudocyst pattern.The signal intensity of DNET was slightly low on T1WI，high on T2WI and low on T2 Flair images.The internal septation and peripheral zone manifest was high signal intensity.DWI showed slightly low in signal intensity and ADC value was high.After administration of contrast，vessels might be seen passing through the lesions and the lesions might present with nodular enhancement with ill-defined margin，and the segmentation may enhance as well.Lesions might show no enhancement at times.There was no mass effect or peritumoral edema.The accompanied cortical dysplasia was revealed and compression of the adjacent cranial bone was seen.Conclusion：DNET demonstrates specific features on MRI，increasing diagnostic accuracy of DNET will be significantly beneficial to clinical prognosis.

【Key words】 Neurons tumor； Mixed neurons tumor； Magnetic resonance imaging

First-authors address：The First Hospital of Quanzhou Affiliated Fujian Medical University，Quanzhou 362000，China

doi：10.14033/j.cnki.cfmr.2016.6.032

不良性神经上皮肿瘤（dysembryoplastic neuroepithelial tumor，DNET）是少见神经上皮源性良性肿瘤，术后预后好，影像学较具有特征性。总结笔者所在医院7例有病理诊断的DNET，结合文献探讨此病MRI特征。

1 资料与方法

1.1 一般资料

搜集2006年1月-2014年7月，经手术病理证实为DNET的7例患者，男5例，女2例，年龄4～20岁，平均13岁。患者均以抽搐为症状就诊，病史半个月～9年。

1.2 方法

7例患者均行MRI平扫+增强扫描，采用GE Signa 1.5T磁共振扫描仪，头部线圈扫描，横轴位T1WI、T2WI、T2Flair、DWI和ADC，矢状位T1WI，层厚5 mm，间隔1.5 mm。增强MRI使用Ga-DTPA，剂量为0.1 mmol/kg，行T1WI轴、冠、矢状位扫描。

2 结果

病变数量：7例患者，均为单发病灶。病变部位：7例均位于幕上，4例位于顶叶，2例位于颞叶，1例位于额叶。病变形态：三角型，基底部朝向脑表面。最大径约1～5.5 cm。MRI表现：7例呈类囊肿……