血清孕酮、β—HCG联合检测在早期先兆流产诊断中的应用分析

张惠

【摘 要】目的：通过本研究分析探讨血清孕酮、β-HCG联合检测在早期先兆流产诊断中的应用效果，并阐述其诊断优势和必要性。方法：选择2017年1月至2018年1月在我院接受治疗的80例早期先兆流产患者作为实验组，选择同时期在我院接受检查的80例正常孕妇作对照组。对比两组孕妇血清孕酮、β-HCG含量，并对确诊的早期先兆流产孕妇，采用联合与单独测定血清孕酮、β-HCG含量，进行早期先兆流产诊断，分析其在早期先兆流产诊断中的应用价值。 结果：实验组孕妇血清孕酮、β-HCG含量明显低于对照组；对80例早期先兆流产孕妇进行血清孕酮、β-HCG含量联合检测与单独检测，联合诊断正确率为93.75%，孕酮指标检测准确率为76.25%，β-HCG指标检测准确率为65%，联合诊断准确率与单独诊断准确率相比，p<0.05，差异极显著，具有统计学意义。 结论：前血清孕酮、β-HCG联合检测在早期先兆流产诊断中效果显著，值得推广应用。

【关键词】 血清孕酮；联合；β-HCG；早期先兆流

[Abstract] Objective：Through this study， we discussed the effect of combined detection of serum progesterone and beta -HCG in the diagnosis of early threatened abortion， and expounded the advantages and necessity of its diagnosis.Method：80 cases of Early Threatened Abortion in our hospital from January 2017 to January 2018 were selected as experimental group， and 80 normal pregnant women in our hospital were selected as control group at the same time. The content of progesterone and beta -HCG in serum of two groups of pregnant women was compared and the content of serum progesterone and beta -HCG was measured by combined and separate determination of serum progesterone and beta -HCG in pregnant women with early threatened abortion， and the diagnostic value of early threatened abortion was analyzed.Result：The content of progesterone and beta -HCG in the serum of pregnant women in the experimental group was significantly lower than that of the control group. The combined detection of serum progesterone and beta -HCG in 80 pregnant women with early threatened abortion， the correct rate of combined diagnosis was 93.75%， the accuracy rate of progesterone index was 76.25%， the accuracy rate of the beta -HCG index was 65%， and the combined diagnostic accuracy rate and the single diagnostic rate were alone. The accuracy of diagnosis was significantly higher than that of p<0.05， and the difference was statistically significant.Conclusion：The combined detection of serum progesterone and beta -HCG has significant effect in the early diagnosis of threatened abortion， and is worthy of popularization and application.

[keyword] serum progesterone， combination， beta -HCG， early warning flow

【中圖分类号】R714.21 【文献标识码】A 【文章编号】2095-6851（2018）05--01

引言

流产属于妇科常见疾病，包括一系列过程，根据不同的阶段，主要分为先兆流产、难免流产、不全流产、完全流产、过期流产。妊娠于28周前终止者称为流产。如在妊娠12周前自然终止者称早期流产，在妊娠13～27周自然终止者为晚期流产[1]。临床上，根据不同阶段，分别采取不同的诊断方式。但是如果诊断失误，导致流产现象处理不当或处理不及时，可能遗留生殖器官炎症，或因大出血而危害孕妇健康，甚至威胁生命。

本研究分别检测了两组孕妇血清孕酮、β-HCG含量，比较两组孕妇血清孕酮、β-HCG含量差异。对确诊的早期先兆流产孕妇，采用联合与单独测定法测定孕妇血清孕酮、β-HCG含量，进行早期先兆流产诊断，并进行了诊断准确率的比较，为孕妇早期先兆流产的诊断奠定了一定的研究基础。……