腹腔镜前列腺癌根治术治疗早期局限性前列腺癌的效果

杨玥

[摘要]目的 探討临床收治的早期局限性前列腺癌应用腹腔镜前列腺癌根治术治疗的临床效果。方法 选择我院泌尿外科2016年6月～2017年6月收治的62例早期局限性前列腺癌患者作为研究对象，按照随机数字表法分为观察组（31例）对照组（31例），观察组采用腹腔镜前列腺癌根治术治疗，对照组采用传统开放手术治疗，对比两组手术情况、术后尿流动力学指标。结果 观察组手术操作用时、术后胃肠功能恢复时间、引流管拔除时间、平均住院时间均短于对照组（P<0.05），术中出血量少于对照组（P<0.05）。观察组术后尿流动力学指标膀胱顺应性（BC）、残余尿量（PVR）、最大尿流率（Qmax）等检测结果均优于对照组（P<0.05）。观察组术后并发症发生率明显低于对照组，随访6个月生活质量评分明显高于对照组，差异均有统计学意义（P<0.05）。结论 对临床收治的早期局限性前列腺癌应用腹腔镜前列腺癌根治术方案治疗，可显著改善手术质量，加快康复进程，改善尿流动力学，提高远期生存质量，有较高安全性，有较高推广应用价值。

[关键词]早期局限性前列腺癌；腹腔镜前列腺根治术；效果观察

[中图分类号] R737.25 [文献标识码] A [文章编号] 1674-4721（2018）5（b）-0082-03

Effect of laparoscopic radical resection of prostate cancer in the treatment of early localized prostate cancer

YANG Yue

Department of Urology，Affiliated General Hospital of Tiefa Coal Industry Group of Shenyang Medical College，Liaoning Province，Tieling 112700，China

[Abstract]Objective To investigate the clinical efficacy of laparoscopic radical resection of prostate cancer in the patients with early localized prostate cancer.Methods Sixty-two patients with early-stage localized prostate cancer who were admitted to the department of urology in our hospital from June 2016 to June 2017 were selected as the study subjects.According to the random number table method，they were divided into observation group （31 cases） and control group （31 cases）.The observation group was given laparoscopic radical resection of prostate cancer.The control group was given traditional open surgery for treatment.The operation situation and postoperative urodynamic parameters were compared between the two groups.Results Compared with the control group，the time of surgical operation，bleeding time during the surgical operation，the recovery time of postoperative gastrointestinal function，the removal time of drainage tube，and the average length of hospital stay in the observation group were shorter than those in the control group，bleeding time during the surgical operation was lesser than those in the control group and the differences were statistically significant （P<0.05）.The testing results of postoperative urodynamic parameters such as BC，PVR，Qmax in the observation group were all better than those in the control group after the surgery，and the difference was statistically significant（P<0.05）.The postoperative complication rate in the observation group was significantly lower than that in the control group.The quality of life scores at the 6-month follow-up period were significantly higher than those in the control group，and the differences were statistically significant（P<0.05）.Conclusion For the patients with early localized prostate cancer who have undergone clinical treatment，the application of laparoscopic radical section of prostate cancer can significantly improve the quality of surgery，accelerate the recovery process，improve urodynamics，improve long-term quality of life，and have a high degree of safety，which has a higher value of promotion and application.

[Key words]Early localized prostate cancer；Laparoscopic radical resection of prostate cancer；Effect observation

临床男性泌尿系统恶性肿瘤领域，前列腺癌发病率居较高水平，严重威胁到患者生命安全。近年随着人口老龄化规模日趋扩大，加之不良饮食及生活行为增多，本病发生率呈显著上升趋势[1-2]。局限性前列腺癌指癌灶尚未将包膜浸透，且未向区域淋巴结和远处转移的一种病理类型，手术为首选治疗方案[3]。但传统开放性手术易诱导吻合口狭窄、持续性尿失禁等多种并发症发生，随着微创医学研究的深入，腹腔镜前列腺癌根治术逐渐应用本病的治疗，取得了理想效果。本研究对腹腔镜前列腺癌根治术治疗早期局限性前列腺癌的效果进行探讨，现报道如下。

1资料与方法

1.1一般资料

选择我院泌尿外科2016年6月～2017年6月收治的62例早期局限性前列腺癌患者作为研究对象，术前均经病理证实，肿瘤于包膜内局限，无远处转移的情况。……