慢性失眠经颅磁刺激治疗的近期效果研究

何婉婷　甘晓文

【摘要】 目的：研究与分析慢性失眠经颅磁刺激治疗的近期效果。方法：选取本院收治的慢性失眠患者100例为研究对象。按照随机数字表法将其分为对照组和观察组，各50例。患者均接受睡眠教育，对照组采取劳拉西泮口服治疗，观察组在对照组基础上采取经颅磁刺激治疗，均治疗15 d。比较两组治疗前后匹兹堡睡眠质量指数（PSQI）评分、治疗效果及不良反应。结果：治疗后2、4周，观察组PSQI指数评分均低于对照组，比较差异均有统计学意义（P<0.05）；观察组治疗总有效率为96.0%，高于对照组的80.0%（P<0.05）；观察组不良反应发生率为6.0%，而对照组未发生任何不良反应，比较差异无统计学意义（P>0.05）。结论：慢性失眠经颅磁刺激治疗可显著提升患者睡眠质量，且不良反应相对较少，同时具有无创、无痛、安全、经济等优势，因此值得临床应用推广。

【关键词】 慢性失眠； 经颅磁刺激； 近期效果

Study on the Short-term Effects of Chronic Insomnia Transcranial Magnetic Stimulation/HE Wanting，GAN Xiaowen.//Medical Innovation of China，2018，15（16）：0-040

【Abstract】 Objective：To study and analyze the short-term effects of transcranial magnetic stimulation for chronic insomnia.Method：A total of 100 patients with chronic insomnia treated in our hospital were selected.According to the random number table method，they were divided into control group and observation group，50 cases in each group.All patients were given sleep education，the control group was treated with Lorazepam，and observation group was treated with transcranial magnetic stimulation on the basis of control group，they were treated for 15 d.The Pittsburgh sleep quality index（PSQI） score before and after treatment，therapeutic effect and adverse reactions were compared between two groups.Result：After treatment 2 and 4 weeks，the PSQI index scores in observation group were lower than those of control group，the differences were statistically significant（P<0.05）.The total effective rate of observation group was 96.0%，which was higher than 80.0% of control group（P<0.05）.The incidence of adverse reactions in observation group was 6.0%，while there was no adverse reaction in control group，the difference was not statistically significant（P>0.05）.Conclusion：The treatment of chronic insomnia by transcranial magnetic stimulation can significantly improve the quality of sleep in patients with less adverse reactions，and has the advantages of noninvasive，painless，safe，economic and so on.Therefore，it is worthy of clinical application.

【Key words】 Chronic insomnia； Transcranial magnetic stimulation； Recent results

First-authors address：Seventh Peoples Hospital of Dongguan，Dongguan 523230，China

doi：10.3969/j.issn.1674-4985.2018.16.011

在人的一生中，睡眠占據了三分之一的时间，而在睡眠充足的情况下，其才能更好的完成各种社会活动，并达到较高的生活质量，因此睡眠是维持人健康不可或缺的重要生理过程[1]。在临床上，失眠是一种较为常见的心理生理疾患，且是一种主观体验，其以睡眠数量和质量因睡眠维持困难或入睡困难等影响而无法满足正常生理需求，并使得白天社会功能受到影响为主要特征[2-3]。对于人而言，长时间失眠会严重影响其正常生活和工作，甚至还会造成一些意外事故。而针对慢性失眠症，临床以往主要采取药物治疗，但易引起各种不良反应，如记忆力下降、戒断反应、对镇静药物依赖性、耐药性等[4]。因此本文即对慢性失眠经颅磁刺激治疗的近期效果进行了研究与分析，现报道如下。……