刘延媛 刘汉冕 陈杏波
【摘要】 目的:分析无创血流动力学参数、左室射血分数联合BNP水平检测评估心力衰竭患者血流动力学的价值。方法:选取2013年6月-2017年6月本院收治的68例心力衰竭患者为研究对象,检测患者无创血流动力学参数、左室射血分数联合BNP水平,并分析心力衰竭患者的血流动力学评估价值。结果:随着心力衰竭患者血中BNP水平升高,其房缩波波幅(WA)、舒张功能指数(O/C)、肺动脉楔压(PCAP)、总外周阻力(TPR)水平均顯著升高(P<0.05);每搏做功(SW)、搏功指数(SWI)、每分做功(CW)、室缩波波幅(C)、心搏出量(SV)、心输出量(CO)、心脏指数(CI)及心缩力指数(HI)水平均显著降低(P<0.05)。BNP与WA、O/C、PCAP及TRP水平均呈显著正相关关系(P<0.05),与SW、SWI、CW、C、SV、CO、CI及HI水平均呈显著负相关关系(P<0.05)。随着LVEF水平升高,WA、O/C、TRP及PCAP均显著降低(P<0.05),CW、SW、SWI、SV、CO、CI、HI及C水平均显著升高(P<0.05);LVEF与患者WA、O/C、PCAP及TPR水平均呈显著负相关关系(P<0.05),与SW、SWI、CW、C、SV、CO、CI及HI水平均呈显著正相关关系(P<0.05)。结论:心力衰竭患者采用无创血流动力学参数、左室射血分数联合BNP水平检测后可有效评估患者血流动力学指标,可用于评估患者病情变化,具有较高的临床应用价值。
【关键词】 无创血流动力学参数; 左室射血分数; BNP水平; 心力衰竭; 血流动力学
The Value of Noninvasive Hemodynamic Parameters,Left Ventricular Ejection Fraction Combined with BNP Level Monitoring to Assess the Value of Hemodynamics in Patients with Heart Failure/LIU Yanyuan,LIU Hanmian,CHEN Xingbo.//Medical Innovation of China,2018,15(14):041-045
【Abstract】 Objective:To analyze noninvasive hemodynamic parameters,left ventricular ejection fraction (LVEF) combined with BNP level monitoring to evaluate hemodynamics in patients with heart failure.Method:68 patients with heart failure were selected in our hospital from June 2013 to June 2017 as the subjects.The noninvasive hemodynamic parameters,left ventricular ejection fraction and BNP levels were detected, and the hemodynamic evaluation value of heart failure patients was analyzed.Result:With the increase of serum BNP level in patients with heart failure,the levels of WA,O/C,PCAP,TPR were significantly higher(P<0.05),the levels of SW,SWI,CW,C,SV,CO,CI,HI were significantly decreased(P<0.05).There were significant positive correlations between BNP and WA,O/C,PCAP,TRP(P<0.05),there were negative correlations between BNP and SW,SWI,CW,C,SV,CO,CI and HI(P<0.05).With the increase of LVEF level,the levels of WA,O/C,TRP,PCAP were decreased significantly(P<0.05),the levels of CW,SW,SWI,SV,CO,CI,HI,C were significantly increased(P<0.05).There were significant negative correlations between LVEF and WA,O/C,PCAP,TPR(P<0.05),there were significant positive correlations between LVEF and SW,SWI,CW,C,SV,CO,CI,HI(P<0.05).Conclusion:Heart failure patients with noninvasive hemodynamic parameters and left ventricular ejection fraction combined with BNP level monitoring can effectively evaluate hemodynamic indexes,and can be used to assess the patients condition changes,so it has high clinical value.
【Key words】 Noninvasive hemodynamic parameters; Left ventricular ejection fraction; BNP level; Heart failure; Hemodynamics
First-authors address:Huizhou Central Peoples Hospital,Huizhou 516001,China
doi:10.3969/j.issn.1674-4985.2018.14.010
心力衰竭是临床中较为常见的疾病,其主要由多种心血管疾病造成的复发综合征,多为各种心血管系统疾病终末期表现,临床中具有较高的死亡率及发病率[1]。有研究结果显示,心力衰竭患者死亡率與肿瘤相似,目前已成为严重威胁人们健康的主要因素,如何有效改善患者预后质量,降低死亡率,具有十分重要的临床意义[2]。有研究结果显示,导致每例患者心力衰竭发生、发展原因及关键环节存在一定差异,因而如何实现有效准确判断及评估具有十分重要的意义[3]。目前临床中常采用超声、X线机、BNP等理化检查手段对患者进行检查,其中BNP检测及超声检查更为普遍,其准确性受到广大医护工作人员认可[4]。但阻抗法无创血流动力学检测这种敏感性较高的方法在临床中应用较少[5]。本院近年来采用阻抗血流图检测仪对心力衰竭患者的无创血流动力学指标进行分析,并同期检测BNP水平及心脏超声测定。……