利用高频彩超评估肾透析患者颈动脉内中膜厚度改变的研究

2018-09-03 10:44:52陈美珊孙容容倪惜芝
中国医学创新 2018年16期

陈美珊 孙容容 倪惜芝

【摘要】 目的:探讨长期透析患者頸动脉内膜的变化及斑块的形成,为深入研究肾透析患者病理发展提供理论依据。方法:选取2016年10月-2017年12月本院收治的50例肾透析患者为研究对象,按透析时间长短分为透析第一年组(17例)、透析第二年组(17例)与透析第三年或更长组(16例)。应用彩色多普勒超声诊断仪检测患者颈动脉内中膜厚度(IMT)、颈动脉内径、颈动脉斑块情况及血流动力学指标。结果:随着透析时间增加,患者颈动脉内中膜厚度逐年上升、颈动脉内径与颈动脉血流速度逐年减小,患者颈动脉斑块发生率逐年增加,患者直径狭窄率逐年增加,差异均有统计学意义(P<0.05)。结论:患者颈动脉内中膜厚度、颈动脉内径、颈动脉斑块情况、颈动脉血流速度及动脉直径狭窄率与患者透析时间长短密切相关,长时间透析患者有并发颈动脉狭窄及动脉粥样硬化的可能。

【关键词】 高频彩超; 肾透析; 颈动脉斑块

Study on Change of Thickness of Carotid Artery in Patients with Renal Dialysis with High Frequency Ultrasound/CHEN Meishan,SUN Rongrong,NI Xizhi,et al.//Medical Innovation of China,2018,15(16):-113

【Abstract】 Objective:To explore the changes of carotid intima and the formation of plaque in long-term dialysis patients,and to provide theoretical basis for the in-depth study of the pathological development of renal dialysis patients.Method:A total of 50 cases of renal dialysis patients in our hospital from October 2016 to December 2017 were divided into the first year of dialysis group,the second year of dialysis group,the third year or longer of dialysis group.Color doppler ultrasonography was used to detect IMT,carotid artery,carotid artery plaque and hemodynamic index.Result:With the increase of dialysis time,IMT was increased year by year,CADIA and carotid artery blood flow velocity were decreased year by year,the incidence of carotid plaque was increased year by year,the diameter stenosis rate was increased year by year,the differences were statistically significant(P<0.05).Conclusion:IMT,CADIA,carotid artery plaque and carotid artery blood flow velocity is closely related to the length of time of renal dialysis,long-term renal dialysis patients are complicated with carotid stenosis and atherosclerosis.

【Key words】 High frequency color ultrasound; Renal dialysis; Carotid artery plaque

First-authors address:Fuyong Peoples Hospital Baoan District,Shenzhen 518103,China

doi:10.3969/j.issn.1674-4985.2018.16.033

早期检测并评价颈动脉内中膜发生发展及其影响因素,并采取相应的防治措施,以减缓乃至逆转动脉硬化的发生发展,是防治维持性血液透析患者心脑血管疾病发病率的重要目标。维持性血液透析时间长短和其他相关因素对肾透析患者颈动脉内膜增厚及动脉粥样硬化的影响有待于进一步观察及研究[1-4]。高频彩超是动态监测颈动脉内中膜变化最快最有效的科学手段,本研究旨在探讨长期透析患者颈动脉内膜的变化及斑块的形成,为临床提供更多有价值的信息,也为无临床症状的高危人群的预后提供帮助[3-7],现报道如下。

1 资料与方法

1.1 一般资料 选取2016年10月-2017年12月本院收治的50例肾透析患者为研究对象,按透析时间长短分为透析第一年组(17例)、透析第二年组(17例)与透析第三年或更长组(16例)。……

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