宫腔镜电切术联合左炔诺孕酮宫内缓释系统治疗子宫内膜息肉的临床治疗效果

林瑞莲 彭明健 黄文蓉

【摘要】 目的：探究宫腔镜电切术联合左炔诺孕酮宫内缓释系统治疗子宫内膜息肉的临床治疗效果。方法：将在笔者所在医院接受治疗的72例子宫内膜息肉患者按照入院顺序分为联合组和对照组，每组36例。所有患者均采用宫腔镜电切术进行治疗，联合组在此基础上配合左炔诺孕酮宫内缓释系统进行治疗。比较两组患者治疗前及治疗后12个月子宫内膜厚度、并发症发生率和复发率。结果：治疗后12个月，联合组子宫内膜厚度明显低于对照组，差异有统计学意义（P<0.05）。联合组并发症发生率、复发率分别为13.89%、2.78%，均顯著低于对照组的38.89%、16.67%，差异有统计学意义（P<0.05）。结论：宫腔镜电切术联合左炔诺孕酮宫内缓释系统对子宫内膜息肉患者的治疗效果确切，可有效改善子宫内膜厚度，并减少并发症的发生，降低疾病复发的风险。

【关键词】 宫腔镜电切术 左炔诺孕酮宫内缓释系统 子宫内膜息肉 治疗效果

doi：10.14033/j.cnki.cfmr.2019.28.069 文献标识码 B 文章编号 1674-6805（2019）28-0-02

Effect of Hysteroscopic Electrotomy Combined with Levonorgestrel Intrauterine Sustained Release System in the Treatment of Endometrial Polyp/LIN Ruilian， PENG Mingjian， HUANG Wenrong. //Chinese and Foreign Medical Research， 2019， 17（28）： -163

[Abstract] Objective： To investigate the clinical effect of hysteroscopic electrotomy combined with levonorgestrel intrauterine sustained release system in the treatment of endometrial polyp. Method： A total of 72 cases of patients with endometrial polyp treated in our hospital were divided into the combined group and the control group according to the order of admission， with 36 cases in each group. All patients were treated with hysteroscopic electrotomy， and the combined group treated with the levonorgestrel intrauterine sustained release system on this basis. The thickness of endometrium before and 12 months after treatment， complication rate and recurrence rate were compared between the two groups. Result： At 12 months after treatment， the thickness of endometrium of the combined group was significantly lower than that of the control group， the difference was statistically significant （P<0.05）. The complication rate and recurrence rate in the combined group were 13.89% and 2.78%， respectively， which were significantly lower than 38.89% and 16.67% in the control group， the differences were statistically significant （P<0.05）. Conclusion： Hysteroscopic electrotomy combined with levonorgestrel intrauterine sustained release system is effective in treating endometrial polyps， which can effectively improve endometrium thickness， and reduce complications and reduce the risk of disease recurrence.

[Key words] Hysteroscopic electrotomy Levonorgestrel intrauterine sustained release system Endometrial polyps Therapeutic effect

First-authors address： Longyan Second Hospital， Longyan 364000， China

子宫内膜息肉是一种高发于育龄妇女的妇科常见疾病，患者可出现月经紊乱、异常子宫出血、不孕等情况，对患者的正常生活和身体健康造成严重影响[1]。目前，临床上治疗子宫内膜息肉的主要手段为宫腔镜电切术，但因术后复发率较高，故治疗效果不佳。左炔诺孕酮宫内缓释系统（LNG-IUS）可对子宫内膜的激素水平进行调节，从而对内膜发挥显著的抑制作用[2]。鉴于此，本研究对宫腔镜电切术联合左炔诺孕酮宫内缓释系统在子宫内膜息肉患者中的应用价值进行了观察，获得了满意的效果，具体报告如下。

1 资料与方法

1.1 一般资料

选择2016年1月-2018年1月笔者所在医院收治的子宫内膜息肉患者72例，纳入标准：无生育要求。排除标准：（1）合并心脏病、糖尿病;（2）合并精神、意识障碍。按照入院顺序分为联合组和对照组，各36例。……