小儿核磁共振检查中睡眠剥夺联合镇静剂应用效果分析

王海兰 韩颖 方丽莹

【摘要】 目的：研究小儿核磁共振检查（magnetic resonance imaging，MRI）中睡眠剥夺联合镇静剂的应用效果。方法：选取2017年3月-2018年3月在本院进行MRI的106例患儿为研究对象，根据双盲随机分组原则分为对照组和观察组，每组各53例。对照组在MRI前0.5 h予以水合氯醛灌肠，观察组先进行睡眠剥夺，再在MRI前半个小时进行水合氯醛灌肠。将两组灌肠操作失败率、配合程度、用药后入睡时间、药物制动效果、一次性检查成功率进行比对。结果：观察组灌肠操作失败率3.77%低于对照组20.75%，差异有统计学意义（P<0.05）;灌肠操作配合良好率73.58%、药物制动显效率92.45%、一次性检查成功率96.23%均高于对照组50.94%、69.81%、75.47%，差异均有统计学意义（P<0.05）;观察组用药后入睡时间（11.05±4.68）min短于对照组（23.15±8.20）min，差异有统计学意义（P<0.05）。结论：睡眠剥夺联合水合氯醛灌肠在小儿MRI中的镇静效果较好，有助于患儿配合度和检查成功率的提高。

【关键词】 小儿; 核磁共振检查; 睡眠剥夺; 镇静剂

【Abstract】 Objective：To study the effect of sleep deprivation combined with tranquilizer on magnetic resonance imaging（MRI）in children.Method：106 children underwent MRI in our hospital from March 2017 to March 2018 were selected as research objects.They were divided into control group and observation group according to the principle of double blind randomized grouping，53 cases in each group.The control group was given enema with chloral hydrate half an hour before MRI，the observation group was given sleep deprivation first，and then was given enema with chloral hydrate half an hour before MRI.The failure rate of enema，the degree of cooperation，the time of falling asleep after medication，the effect of drug immobilization and the success rate of one-off examination were compared between the two groups.Result：The failure rate of enema in the observation group was 3.77% lower than the control group of 20.75%，the difference was statistically significant（P<0.05）;the good cooperation rate of enema was 73.58%，the apparent efficiency rate of drug immobilization was 92.45% and the success rate of one-off examination was 96.23%，they were higher than the control group of 50.94%，69.81% and 75.47%，the differences were statistically significant（P<0.05）.The time of falling asleep in the observation group was（11.05±4.68）min lower than the control group of（23.15±8.20）min，the difference was statistically significant（P<0.05）.Conclusion：Sleep deprivation combined with chloral hydrate enema has a better sedation effect in children with MRI.It is helpful to improve the cooperation degree and the success rate of examination.

【Key words】 Children; Magnetic resonance imaging; Sleep deprivation; Sedative

First-authors address：Longgang Central Hospital，Shenzhen 518116，China

doi：10.3969/j.issn.1674-4985.2019.16.027

隨着现代影像技术的迅猛发展，核磁共振检查（magnetic resonance imaging，MRI）在临床中应用广泛，该影像学检查方式具有图像清晰度高且无放射性损害的优点，应用在婴幼儿疾病的诊断和评估中作用较大[1]。MRI的扫描时间长，且仪器设备的噪声较大，小儿不能较好地适应周围环境，且对外界刺激具有较强的敏感性，容易出现躁动不安、哭闹的情况，导致MRI不能顺利完成，因此选择合理的方式提高镇静效果十分重要[2-3]。选取2017年3月-2018年3月本院收治的患儿106例开展本次研究，目的在于分析睡眠剥夺联合镇静剂的效果，现报道如下。

1 资料与方法

1.1 一般资料 选取2017年3月-2018年3月本院收治的患儿106例。纳入标准：生命体征稳定;无MRI禁忌证。排除标准：存在呼吸系统、循环系统疾病;存在药物使用禁忌证;长期使用过鲁米那、硝西泮等镇静药物。根据双盲随机分组原则分为对照组和观察组。家属均知情同意并签署知情同意书，本研究经医院伦理学委员会批准。……