左心室相关指标及凝血因子与冠心病介入治疗预后的关系探究

吴伟生

【摘要】 目的：探究左心室相关指标及凝血因子与冠心病介入治疗预后的关系。方法：选取2016年7月-2019年7月本院收治的90例冠心病介入治疗患者作为观察组，另选取同时期90例健康者作为对照组。检测与比较两组左心室相关指标及凝血因子，同时比较观察组不同预后情况（不良心血管事件）者的检测水平，并采用Logistic多元回归分析处理上述研究指标与冠心病介入治疗预后的关系。结果：观察组左室射血分数（LVEF）显著低于对照组（P<0.05），其他左心室相关指标及凝血因子均显著高于对照组（P<0.05）。观察组中不同预后情况（不良心血管事件）者的检测指标水平比较，差异均有统计学意义（P<0.05），不同心血管事件者的检测指标水平比较，差异均无统计学意义（P>0.05）。Logistic多元回归分析显示，上述左心室相关指标及凝血因子均与冠心病介入治疗预后有密切的关系（P<0.05）。结论：左心室相关指标及凝血因子与冠心病介入治疗预后有密切的关系，因此上述指标在冠心病介入治疗患者中的监测价值较高。

【关键词】 左心室相关指标 凝血因子 冠心病 介入治疗 预后

[Abstract] Objective： To investigate the relationship between left ventricular related indexes， coagulation factors and prognosis of interventional therapy for coronary heart disease. Method： A total of 90 patients with interventional therapy for coronary heart disease from July 2016 to July 2019 were selected as the observation group， 90 healthy persons at the same time were selected as the control group. The left ventricular related indexes and coagulation factors of two groups were compared， and the detection levels of the observation group with different prognosis situation （major adverse cardiovascular events） were compared， and the relationship between those study indexes and prognosis of interventional therapy for coronary heart disease were analyzed with Logistic multiple regression analysis. Result： The left ventricular ejection fractions （LVEF） of the observation group was significantly lower than that of the control group （P<0.05）， other left ventricular related indexes and coagulation factors were all significantly higher than those of the control group （P<0.05）. The detection levels of the observation group with different prognosis situation （major adverse cardiovascular events） were compared， there were all statistically significant differences （P<0.05）. There were no statistically significant differences in the detection level of patients with different cardiovascular events （P>0.05）. Logistic multiple regression analysis showed those left ventricular related indexes and coagulation factors all had close relationship to the prognosis of interventional therapy for coronary heart disease （P<0.05）. Conclusion： The left ventricular related indexes and coagulation factors all have close relationship to the prognosis of interventional therapy for coronary heart disease， so the monitoring value of those indexes in the patients with interventional therapy for coronary heart disease are higher.

冠心病在我國具有极高的发病率，而介入治疗在本病的治疗中起着极为重要的作用，因此关于冠心病介入治疗相关的研究是临床重点。而与冠心病介入治疗预后的研究是重中之重，关于本类患者预后的相关指标研究则有助于患者预后的了解，对防控性措施的制定也有积极的参考作用[1-2]。左心室相关指标及凝血因子作为在心脑血管疾病中研究较多的指标，其在冠心病患者中的表达研究可见[3-4]，但是在介入治疗患者预后中的检测意义研究未见。因此，本研究就左心室相关指标及凝血因子与冠心病介入治疗预后的关系进行探究。现报道如下。

1 资料与方法

1.1 一般资料 选取2016年7月-2019年7月本院收治的90例冠心病介入治疗患者作为观察组，同时期90例健康者为对照组。……