支气管扩张剂联合吸入性糖皮质激素治疗慢阻肺的效果

曾丽赣

[摘要] 目的 研究慢性阻塞性肺疾病患者采用支氣管扩张剂联合吸入性糖皮质激素治疗的疗效及对生活质量的影响。方法 选取2017年1月～2020年1月我院收治的慢性阻塞性肺疾病患者80例，随机分为对照组和观察组，每组40例。对照组单用支气管扩张剂治疗，观察组采用支气管扩张剂联合吸入性糖皮质激素治疗。比较两组的治疗效果及治疗后的生活质量，并比较两组患者的满意度情况。 结果 观察组治疗总有效率为95.00%，高于对照组的75.00%，有显著差异（P<0.05）。治疗后，观察组躯体（23.81±2.85）分、认知（23.05±2.47）分、情绪（25.06±2.93）分、角色（20.94±2.75）分、社会功能（24.02±2.66）分、总体健康（26.86±2.83）分，均高于对照组，有显著差异（P<0.05）。观察组患者的总满意率为90.00%，高于对照组患者的70.00%，有显著差异（P<0.05）。 结论 在慢性阻塞性肺疾病患者的治疗当中，采用支气管扩张剂联合吸入性糖皮质激素治疗，能够取得理想的临床疗效，同时对于患者生活质量也有积极的影响。

[关键词] 慢性阻塞性肺疾病;支气管扩张剂;吸入性糖皮质激素;生活质量

[中图分类号] R563.9          [文献标识码] B          [文章编号] 1673-9701（2020）17-0132-03

Effect of bronchodilator combined with inhaled glucocorticoid in the treatment of chronic obstructive pulmonary disease

ZENG Ligan

Department of Respiratory Medicine and Critical Care Medicine， the Fourth Affiliated Hospital of Nanchang University， Nanchang   330000， China

[Abstract] Objective To study the efficacy and quality of life of patients with chronic obstructive pulmonary disease（COPD） who were treated with bronchodilator combined with inhaled corticosteroids. Methods 80 patients with COPD who were admitted to our hospital from January 2017 to January 2020 were selected and randomly divided into the control group and the observation group， with 40 cases in each group. The control group was given bronchodilator alone， and the observation group was given bronchodilator combined with inhaled glucocorticoid. The therapeutic effect and quality of life after treatment were compared between the two groups， and the satisfaction was also compared between the two groups of patients. Results The total effective rate of treatment in the observation group was 95.00%， higher than that of 75.00% in the control group， and the difference was significant（P<0.05）. After treatment， the score of physical body was（23.81±2.85）， the cognition score was（23.05±2.47）， the emotion score was（25.06±2.93）， the role score was（20.94±2.75）， the score of social function was（24.02±2.66）， and the score of overall health was（26.86±2.83） in the observation group， which were higher than those in the control group， and the differences were significant（P<0.05）. The overall satisfaction rate in the observation group was 90.00%， which was higher than that of 70.00% in the control group， and the difference was significant（P<0.05）. Conclusion In the treatment of patients with chronic obstructive pulmonary disease， the use of bronchodilators combined with inhaled glucocorticoid therapy can achieve the desired clinical efficacy， and also have a positive effect on the quality of life of patients.

[Key words] Chronic obstructive pulmonary disease（COPD）; Bronchodilator; Inhaled corticosteroids; Quality of life

慢性阻塞性肺疾病是一种常见的呼吸系统疾病，一般中老年人比较多发。由于气道阻滞影响通气功能，气流流动不畅，进而导致患者容易出现肺气肿、慢性支气管炎等多种并发症[1]。严重时还可能进展为呼吸衰竭，对患者的身体健康和生活质量造成了很大的影响。在临床上，一般采用支气管扩张剂进行治疗，控制症状和病情进展，减少并发症，改善患者预后。但是单独用药效果有限，对患者生活质量改善也不明显。因此，应采取联合用药的方式，采用支气管扩张剂联合吸入性糖皮质激素治疗，从而进一步提升治疗效果，改善患者生活质量。基于此，本文选取2017年1月～2020年1月医院收治的慢性阻塞性肺疾病患者80例，研究慢性阻塞性肺疾病患者给予支气管扩张剂联合吸入性糖皮质激素治疗的临床疗效及对生活质量的影响。……