黄葵胶囊联合尿毒清用于肾功能不全患者的临床效果

谢莹莹 夏燕 张雪梅 潘颖 王东

摘要 目的：探析采取黄葵胶囊联合尿毒清治疗肾功能不全患者的有效性。方法：选取2019年1月至2020年6月马鞍山十七治医院收治的肾功能不全患者60例作为研究对象进行回顾性分析，按照治疗方法不同分成对照组和观察组，每组30例。对照组采用常规西医治疗，观察组给予黄葵胶囊联合尿毒清治疗，比较2组患者血红蛋白（Hb）水平、红细胞计数（RBC）、尿素氮（BUN）、血肌酐（SCr）、不良反应及治疗有效率等指标。结果：与对照组比较，观察组Hb、RBC、BUN、SCr等生化指标改善更明显，差异有统计学意义（P<0.05）;观察组不良反应发生率更低，治疗有效率更高，差异有统计学意义（P<0.05）。结论：采取黄葵胶囊联合尿毒清颗粒治疗肾功能不全能够获得较为理想的效果，用药安全性较高，有极大的推广价值。

关键词 肾功能不全;黄葵胶囊;尿毒清;不良反应;生化指标;安全性;肾功能;治疗效果

Abstract Objective：To explore the efficacy of Huangkui Capsules combined with Niaoduqing in the treatment of renal insufficiency.Methods：A total of 60 patients with renal insufficiency admitted to Ma′anshan Seventeen Hospital from January 2019 to June 2020 were selected as the research objects and were randomly divided into a control group（n=30，treated with conventional Western Medicine）and an observation group（n=30，treated with Huangkui Capsules combined with Niaoduqing）according to different treatment.The levels of hemoglobin（Hb），red blood cell count（RBC），urea nitrogen（BUN），serum creatinine（SCr），adverse reactions and total effective rate etc.of the 2 groups were compared.Results：compared with the control group，Hb，RBC，BUN，SCr and other biochemical indicators in the observation group were improved and the difference was statistically significant（P<0.05）; the incidence of adverse reactions in the observation group was lower，the total effective rate was higher，the difference was statistically significant（P<0.05）.Conclusion：Huangkui Capsules combined with Niaoduqing Granules in the treatment of renal insufficiency can obtain ideal effect with high safety.The medication is safer and has great promotion value.

Keywords Renal insufficiency; Huangkui Capsules; Niaoduqing; Adverse reactions; Biochemical indicators; Safety; Renal function; Therapeutic effects

中图分类号：R289.5;R692文献标识码：Adoi：10.3969/j.issn.1673-7202.2021.10.016

肾功能不全主要是由多种慢性肾脏疾病不断发展导致的，以慢性肾实质性病变为特点，若不进行针对性的及时治疗，会出现肾功能不全症状，进而引起肾衰竭[1]。早期肾功能不全患者主要是通过调整饮食、改变生活方式、药物治疗等措施干预，终末期肾功能不全患者主要是通过血液透析、肾移植等方式治疗，而后者在增加治疗费用的同时，还会使患者出现更多的不良反应[2]。所以，寻求一种及时、有效、经济的治疗方法，延缓肾功能不全的进展，提高患者整体生命质量，是目前肾内科医生关注的重点[3]。近年来，伴随着我国中药制药技术的发展，临床中应用的部分中成药，不仅可促使患者的病情得到有效控制，还能促使患者的相关指标明显改善[4]。我们对马鞍山十七治医院肾功能不全的患者采用黄葵胶囊联合尿毒清颗粒进行治疗。……