胺碘酮联合酒石酸美托洛尔治疗慢性心力衰竭合并快室率心房颤动的疗效改善心功能分析

方婧菲 刘俊伟 谭博

【摘要】目的：分析在慢性心力衰竭合并快室率心房顫动患者中使用胺碘酮联合酒石酸美托洛尔进行治疗的效果。方法：选取我院收治的65例慢性心力衰竭合并快室率心房颤动患者作为研究对象，并将其随机分成33例对照组与32例观察组；对照组使用胺碘酮治疗，观察组采用胺碘酮联合酒石酸美托洛尔进行治疗，对比两组患者的治疗效果。结果：观察组患者治疗前左心室舒张末期容积、左心室射血分数以及左心室收缩末期容积均与对照组无显著差异（P>0.05）。治疗后，观察组患者左心室舒张末期容积显著低于对照组（P<0.05）；观察组左心室收缩末期容积显著低于对照组（P<0.05）；观察组左心室射血分数显著高于对照组（P<0.05）。两组患者治疗前后各项指标均有显著差异（P<0.05）。观察组治疗总有效率为96.88%，对照组为75.76%，观察组显著高于对照组（P<0.05）。结论：对慢性心力衰竭合并快室率心房颤动患者采取胺碘酮、酒石酸美托洛尔联合药物疗法，对于帮助患者恢复心功能水平具有重要作用，治疗有效性较高，可推广。

【关键词】慢性心力衰竭；快室率心房颤动；胺碘酮；酒石酸美托洛尔

[中图分类号]R541.6；R541.75 [文献标识码]A [文章编号]2096-5249（2021）13-0082-02

Amiodarone combined with metoprolol tartrate in the treatment of chronic heart failure combined with fast ventricular rate atrial fibrillation to improve cardiac function

FANG Jing-fei1， LIU Jun-wei1， TAN Bo2 （1.Department of Internal Medicine， Nancheng Hospital， Dongguan City， Dongguan Guangdong 523000， China； 2.Department of Emergency， Maoming People’s Hospital， Maoming Guangdong 525000， China）

[Abstract] Objective： To analyze the effect of amiodarone combined with metoprolol tartrate in patients with chronic heart failure and fast ventricular atrial fibrillation. Methods： 65 patients with chronic heart failure and fast ventricular atrial fibrillation admitted to our hospital were selected as the research objects， and they were randomly divided into 33 control groups and 32 observation groups； the control group was treated with amiodarone and the observation group was treated with amine Iodone combined with metoprolol tartrate was treated to compare the therapeutic effects of the two groups of patients. Results： The left ventricular end-diastolic volume， left ventricular ejection fraction， and left ventricular end-systolic volume before treatment in the observation group were not significantly different from those in the control group（P>0.05）. After treatment， the left ventricular end-diastolic volume and left ventricular end-systolic volume of the observation group were significantly lower than those of the control group（P<0.05）； the left ventricular ejection fraction of the observation group was significantly higher than that of the control group（P<0.05）. There were significant differences in various indicators between the two groups of patients before and after treatment（P<0.05）. The total effective rate of treatment in the observation group was 96.88%， and the control group was 75.76%. The observation group was significantly higher than the control group（P<0.05）. Conclusion： The treatment of amiodarone combined with metoprolol tartrate in patients with chronic heart failure and fast ventricular atrial fibrillation can help to improve the level of cardiac function in patients. It is highly effective and can be promoted.

[Key words] Chronic heart failure； Fast ventricular rate atrial fibrillation； Amiodarone； Metoprolol tartrate

慢性心力衰竭是目前社会人群中十分常见的内科疾病，尤其在不健康的生活方式普遍存在的情况下，该病发病率较高，时常伴随快室率心房颤动等心律失常现象产生，且常常引发患者心悸、头晕、发绀、少尿、无力等并发症，给患者带来较大的生活质量威胁，甚至影响患者生命安全。……