甘婷 汤富友 李静 余雨枫



[摘要]目的系统评价计算机辅助认知训练改善脑卒中患者认知功能的效果。方法检索中英文数据库从建库至2021年2月有关计算机辅助认知训练对脑卒中患者认知功能影响的随机对照研究文献。对文献筛选、质量评价和数据提取后,采用RevMan 5.3软件对纳入文献进行 meta 分析。结果共纳入14篇文献,869例患者。结果显示,计算机辅助认知训练可提高脑卒中患者认知水平,MMSE 评分(MD=3.18,95%CI:1.00~5.35,d=0.004)、MoCA 评分(MD=3.68,95%CI:2.38~4.98,d <0.00001),差异有统计学意义。结论计算机辅助认知训练可改善脑卒中患者认知功能。
[关键词]计算机辅助认知训练;脑卒中;认知功能; meta 分析
[中图分类号] R743.3 [文献标识码] A [文章编号]2095-0616(2021)23-0061-05
Meta -analysis of the effect of computer -assisted cognitive training on cognitive function of stroke patients
GAN Ting TANG Fuyou LI Jing YU Yufeng
Nursing College, Chengdu University ofTraditional Chinese Medicine, Sichuan, Chengdu 610075, China
[Abstract] Objective To systematically evaluate the effect of computer-assisted cognitive training on improving cognitive function of stroke patients. Methods The literature on the effect of computer-assisted cognitive training on cognitive function of stroke patients from the establishment of Chinese and English databases to February 2021 was searched in the databases for randomized controlled studies. After screening and quality evaluation of the literature and data extraction from it, RevMan5.3 software was used for meta-analysis of the included literature. Results A total of 14 papers were included, covering 869 patients. According to the results, computer-assisted cognitive training can improve the cognitive level of stroke patients, the MMSE scores (MD=3.18, 95%CI:1.00-5.35, d=0.004) and the MoCA scores (MD=3.68, 95%CI:2.38-4.98, d <0.00001), and the differences were statistically significant. Conclusion Computer-assisted cognitive training can improve the cognitive function of stroke patients.
[Key words] Computer-assisted cognitive training; Stroke; Cognitive function; Meta-analysis
腦卒中后认知障碍(post-stroke cognitive impairment, PSCI)是指脑卒中后6个月以内,经临床诊断为认知障碍的一系列综合征[1]。在国外,脑卒中后3个月内认知障碍的发生率为69.80%,而我国发生率高达80.97%[2-3]。PSCI 严重影响患者日常生活能力,阻碍患者康复进程,增加残疾率[4-5]。脑卒中后认知功能的康复训练基于健存脑组织的可塑性,对受损较轻的神经进行细胞修复和皮质重建[6]。近年来,计算机与认知康复领域研究的结合发展较为成熟。计算机辅助认知训练已广泛应用于精神分裂症、痴呆、多发性硬化症等患者,并且能在一定程度上改善患者的认知功能[7-9]。但其对 PSCI 患者的真实干预效果存在争议。因此,本研究针对计算机辅助认知训练改善脑卒中患者认知功能进行系统评价,进一步验证干预效果,为临床决策提供证据支持。
1资料与方法
1.1文献纳入与排除标准
纳入标准:①研究对象为经临床诊断为脑卒中患者,年龄……