绿茶饮料用作MRCP对比剂的研究进展

张亚平　周薇　边海山

摘要：尽管MRCP具有多序列、多参数、多方位成像以及较高的软组织分辨力，但在实际工作中发现某些病变与正常组织的T1甚至T2弛豫时间无明显差别。另外，有些病变虽有明显的异常信号，但诊断与鉴别诊断仍较困难，还有些病变较小，平扫不易显示。在这些情况下，我们需要应用引入MRCP对比剂来帮助解决。本文就新型口服阴性对比剂康师傅绿茶饮料应用于MRCP检查的技术原理及在MRCP检查中的良好应用进展进行综述。

关键词：茶饮料;MRCP;对比剂;研究进展

Research progress of green tea beverage as contrast agent of MRCP

Zhang Ya-ping¹，ZHOU Wei²，ZHANG Hong-she¹，FENG Hai-tao¹，XU Tao¹，Bian Hai-shan¹，DONG Ning¹

〔1.Zhuozhou Hospital，Hebei 072750，China2. Department of Stomatology，Baoding Second Central Hospital;2. Hebei 072750，China）

【Abstract】：Although MRCP has multi - sequence，multi - parameter，multi - directional imaging and high resolution of soft tissue，some of them have been found in practice

There was no significant difference in T1 or even T2 relaxation time between lesions and normal tissues. In addition，although some lesions have obvious abnormal signals，but the diagnosis and differential diagnosis is still more difficult，and some lesions are small，plain scan is not easy to show. In these cases，we need to apply the introduction of MRCP contrast agent to help solve. In this paper，the technical principle and good application progress of master Kong green tea beverage，a new oral negative contrast agent，in MRCP examination were reviewed.

【Key words 】Tea beverage;MRCP. Contrast agent;The research progress

磁共振胰膽管造影（magnetic resonance cholangiopancreatography，MRCP）是一种无创伤性新技术，具有简单、快捷、准确率高等特点，无需应用任何造影剂即可立体多角度显示胆道系统，发现胆管结构异常，MRCP敏感度及特异度均较好，准确度较B超及MSCT均高^[1]，目前已经成为无创性评价胰胆管疾病的强有力方法，其诊断性能类似于内镜下逆行胰胆管造影^[2-3]，是行之有效的检查技术，尤其对梗阻性胰胆管疾病的评估具有较高的敏感性、特异性和准确性^[4]。行常规MRCP检查时由于胆道与胰腺病变的影响患者胃肠道内常含有潴留液，不仅影响MRCP的质量，而且易造成误诊^[5]，胃肠道内液体同时显影，影响了对胰胆管的观察，尤其是胃窦与十二指肠横跨过右上腹，其内液体的高信号掩盖和干扰了胆总管中下段的显示，是影响MRCP图像质量的重要原因之一^[6]。MRCP检查结合口服阴性对比剂，可不受胃及肠道等影响因素的困扰^[7]，所以如何筛选出一种相对最为理想的口服阴性对比剂抑制其信号的干扰，无疑是较为重要的。……