“特殊生态环境微生物及次级代谢产物”专辑特邀主编孙承航研究员简介

孙承航，男，1966年7月出生，中国医学科学院北京协和医学院医药生物研究所研究员，博士研究生导师，微生物化学研究室主任。1999年于中国医学科学院&中国协和医科大学获博士学位。以海外研究员和博士后身份，先后在日本北里研究所和约翰霍普金斯大学公共卫生学院从事抗感染相关研究。研究领域：特殊生态环境药用微生物资源勘探和新抗生素发现，具体包括：特殊生态环境放线菌多样性及新颖性研究、放线菌物种鉴定、基于色谱-质谱联用分子网络发现新抗生素、化合物分离纯化与结构鉴定。先后主持“十一五”和“十二五”国家科技重大专项、重大新药创制课题“微生物产物化学研究”和“特境微生物创新药物研究”，中国医学科学院医学与健康科技创新工程服务“一带一路”战略先导科研专项“特殊环境中药用微生物资源发现与利用”，多项国家自然科学基金以及国际合作课题。特境来源药用微生物资源勘探和新抗生素发现代表作如下(*为通讯作者)：

沙漠特境：

1.Shao-wei Liu,Norovsuren Jadambaa,Arina A.Nikandrova,Ilya A.Osterman and Cheng-hang Sun*: Exploring the Diversity and Antibacterial Potentiality of Cultivable Actinobacteria from the Soil of the Saxaul Forest in Southern Gobi Desert in Mongolia.Microorganisms 2022,10: 989.https://doi.org/10.3390/microorganisms10050989.

2.Shao-wei Liu,Ting Wang,Qin-pei Lu,Fei-na Li,Gang Wu,Zhong-ke Jiang,Xugela Habden,Lin Liu,Xiao-lin Zhang,Dmitrii A.Lukianov,Ilya A.Osterman,Petr V.Sergiev,Olga A.Dontsova and Cheng-hang Sun*:Bioprospecting of Soil-Derived Actinobacteria along the Alar-Hotan Desert Highway in the Taklamakan Desert.Frontiers in microbiology 2021,12: 604999，https://doi.org/10.3389/fmicb.2021.604999.

3.Wang Ting,Li Feina,Lu Qinpei,Habden Xugela,Razumova Elizaveta A,Osterman Ilya A,Sergiev Petr V,Dontsova Olga A,You Xuefu,Sun Chenghang*: Studies on diversity,novelty,antimicrobial activity and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected in Taklamakan desert.Journal of Pharmaceutical Analysis.2021,11(2): 241-250.https://doi.org/10.1016/j.jpha.2020.06.004.

红树林特境：

4.Qin-Pei Lu,Yong-Mei Huang,Shao-Wei Liu,Gang Wu,Qin Yang,Li-Fang Liu,Hai-Tao Zhang,Yi Qi,Ting Wang,Zhong-Ke Jiang,Jun-Jie Li,Hao Cai,Xiu-Jun Liu,Hui Luo*and Cheng-Hang Sun*: Metabolomics Tools Assisting Classic Screening Methods in Discovering New Antibiotics from Mangrove Actinomycetia in Leizhou Peninsula.Marine drugs,2021,19: 688.https://doi.org/10.3390/md19120688.

5.Qin-Pei Lu,Jing-Jing Ye,Yong-Mei Huang,Di Liu,Li-Fang Liu,Kun Dong,Elizaveta Andreevna Razumova,Ilya Andreevich Osterman,Petr Vladimirovich Sergiev,Olga Anatolievna Dontsova,Shu-Han Jia,Da-Lin Huang,Cheng-Hang Sun*: Exploitation of Potentially New Antibiotics from Mangrove Actinobacteria in Maowei Sea by Combination of Multiple Discovery Strategies.Antibiotics 2019,8(4): 36; https://doi.org/10.3390/antibiotics8040236.

6.Jiang Zhong-Ke,Tuo Li,Huang Da-Lin,Osterman Ilya A,Tyurin Anton P,Liu Shao-Wei,Lukyanov Dmitry A,Sergiev Petr V,Dontsova Olga A,Korshun Vladimir A,Li Fei-Na,Sun Cheng-Hang*: Diversity,novelty,and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi,China.Frontiers in Microbiology,2018,9: 868.https://doi.org/10.3389/fmicb.2018.00868.

喀斯特洞穴特境：

7.Li Tuo,Lin Guo,Shao-Wei Liu,Jia-Meng Liu,Yu-Qin Zhang,Zhong-Ke Jiang,Xian-Fu Liu,Li Chen,Jian Zu and Cheng-Hang Sun*: Lysinibacter cavernae gen.nov.,sp.nov.,a new member of the family Microbacteriaceae isolated from a karst cave.International Journal of Systematic and Evolutionary Microbiology,2015,65: 3305-3312.https://doi.org/10.1099/ijsem.0.000415.

8.Zhong-ke Jiang,Lin Guo,Chuan Chen,Shao-wei Liu,Lin Zhang,Su-juan Dai,Qi-yang He,Xue-fu You,Xinxin Hu,Li Tuo,Wei Jiang*and Cheng-Hang Sun*: Xiakemycin A,a novel pyranonaphthoquinone antibiotic,produced by the Streptomyces sp.CC8-201 from the soil of a karst cave.The Journal of Antibiotics,2015,68: 771-774.https://doi.org/10.1038/ja.2015.70.

9.Xiao-Jun Li,Su-Juan Dai,Shao-Wei Liu,Jia-Meng Liu,Li Chen,Lin Hu and Cheng-Hang Sun*:Tenggerimyces flavus sp.nov.,isolated from soil in a karst cave and emended description of the genus Tenggerimyces.International Journal of Systematic and Evolutionary Microbiology.2016,66: 1499-1505.https://doi.org/10.1099/ijsem.0.000908.

盐湖特境：

10.Qin Yang,Pu-Yu Guo,Elena Y.Abidueva,Fei- Na Li,Chun- mei Xue,Shao- Wei Liu*,and Cheng-Hang Sun*: Hoyosella lacisalsi sp.nov.,a halotolerant actinobacterium isolated from Lake Gudzhirganskoe.Journal of Systematic and Evolutionary Microbiology.2021,71(12).https://doi.org/10.1099/ijsem.0.005145.

11.Xiao-Jun Li,Jia-Meng Liu,Yue Wu,Wei-Ming Zhang,Jing Li,Shao-Wei Liu,Gang Wu,Lin Hu,Li Chen,Da-Lin Huang,Rong-Feng Li and Cheng-Hang Sun*: Description of Salilacibacter albus gen.nov.,sp.nov.,isolated from a dried Salt Lake and reclassification of Paraglycomyces xinjiangensis Luo et al.2015 as a later heterotypic synonym of Salininema proteolyticum Nikou et al.2015 with emended descriptions of the genus Salininema and Salininema proteolyticum.International Journal of Systematic and Evolutionary Microbiology.2016,66: 2558-2565.https://doi.org/10.1099/ijsem.0.001093.

12.Lin Guo,Li Tuo,Xugela Habden,Yu-qin Zhang,Jia-meng Liu,Zhong-ke Jiang,Shao-wei Liu,Tohty Dilbar*and Cheng-hang Sun*: Allosalinactinospora lopnorensis gen.nov.,sp.nov.,a new member of the family Nocardiopsaceae isolated from soil.International Journal of Systematic and Evolutionary Microbiology,2015,65:206-213.https://doi.org/10.1099/ijs.0.055160-0.