王燕等
摘要:目的 分析新疆地区代谢综合征患者中西北燥证危险因素。方法 在新疆喀什、哈密、乌鲁木齐地区共收集321例代谢综合征患者,共筛选15类变量,计算OR值和95%CI,并用条件Logistic回归分析方法进行单因素及多因素分析。结果 单因素Logistic回归分析结果显示,饮食习惯嗜食肥甘,饮食偏嗜喜辣、喜咸,及吸烟史、高血压是西北燥证危险因素,其OR值分别为0.387、0.071、0.033、2.614、0.440,均P<0.05。多因素Logistic回归分析结果,吸烟史、饮酒史、嗜食肥甘及高血压均进入回归模型,其OR值分别为3.945、4.334、0.370、2.142,均P<0.01。结论 建议代谢综合征患者中嗜食肥甘及喜辣、喜咸者适当调整饮食口味,增加酸味饮食,荤素搭配,戒烟酒,控制血压,可能有助于适应当地气候、生活环境,减少西北燥证的发生,利于疾病康复。
关键词:代谢综合征;西北燥证;危险因素;Logistic回归分析
DOI:10.3969/j.issn.1005-5304.2015.09.005
中图分类号:R259.89 文献标识码:A 文章编号:1005-5304(2015)09-0015-03
Logistic Regression Analysis on Risk Factors of Northwest Dryness Syndrome Among Patients of Metabolic Syndrome in Xinjiang Uygur Autonomous Region WANG Yan, WANG Xiao-zhong, MA Yan, ZHUANG Xiao-fang, GUO Feng, HE Jia-ying (Department of Liver, Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830000, China)
Abstract:Objective To analyze risk factors of northwest dryness syndrome (NDS) among the patients of metabolic syndrome in Xinjiang Uygur Autonomous Region. Methods Totally 321 cases of metabolic syndrome in Kashgar, Hami and Urumqi were collected to filter 15 variables to calculate OR value and 95% CI, and evaluated by single factor and multi-factor analysis by applying conditional Logistic regression analysis. Results Single factor conditional Logistic regression analysis showed that high fat diet, addiction to hot diet, salty diet, smoking history and hypertension were the risk factors of NDS. The OR values of them were 0.387, 0.071, 0.033, 2.614 and 0.440, respectively (P<0.05). Multi-factor conditional Logistic regression analysis showed that smoking history, alcohol drinking history, high fat diet and hypertension were all entered into regression model. The OR values of them were 3.945, 4.334, 0.370 and 2.142, respectively (P<0.01). Conclusion Patients of metabolic syndrome with a high fat, salty and hot diet are suggested to adjust their diet habit by adding sour food, giving up smoking and drinking, and controlling their blood pressure. It will be helpful for them to adapt local climate and living environment, and reduce the attack rate of NDS.
Key words:metabolic syndrome;northwest dryness syndrome;risk factor;Logistic regression analysis
基金項目:国家自然科学基金(81260518)
通讯作者:王晓忠,E-mail:wxz125@sina.com
代谢综合征(metabolic syndrome,MS)是多种代
谢异常聚集于同一个体的病理状态。受地区、种族及经济状况影响,MS的患病率各地存在差异。2005年完
成的一项全国调查显示,15%中国成年人患有MS[1]。2009年北京郊区25~65岁人群流行病学调查显示MS患病率达20.3%[2],2013年上升为26.8%[3]。而2010年新疆和田地区维吾尔族MS患病率即为38.2%[4], 2012年乌鲁木齐市汉族成年人MS患病率为44.0%[5],均远高于全国平均水平。既往研究显示,MS组分高血压与西北燥证相关[6-7]。西北燥证是指发生于以新疆为代表的西北地区,以感受燥邪为主要病因,以口鼻、咽喉、肌肤干燥和干咳、烦躁等各种不适症状为特征的一组中医证候[8]。为进一步明确MS与西北燥证的相关性,本课题组开展了相关流行病学调查工作,现报道如下。
1 资料与方法
1.1 研究对象
收集2012年9月-2013年5月在新疆维吾尔自治区中医医院、喀什地区第一人民医院、哈密地区中心医院就诊的MS患者共321例。其中汉族171例,男性93例(54.39%),女性78例(45.61%),平均年龄(59.11±11.71)岁;……