中药川芎嗪联合硫酸镁治疗妊娠高血压

中药川芎嗪联合硫酸镁治疗妊娠高血压

孙君侠，李建芬，尹金丽，卓会芳，王娜，高辉，毕淑洁

(唐山市协和医院妇产科，河北 唐山 063000)

摘要：目的探究中药川芎嗪联合硫酸镁在妊娠高血压治疗过程中的疗效,为临床治疗妊娠高血压提供依据。方法选取2010年9月—2013年12月间在我院住院治疗的妊娠高血压患者90例，根据治疗方法的不同分为对照组及观察组各45例，其中观察组患者采用中药川芎嗪联合硫酸镁注射液治疗，对照组单纯采用硫酸镁注射液治疗，并观察2组患者治疗的临床效果、有效率以及治疗前后的血浆黏度值。结果观察组总有效率(97.8%)明显高于对照组(86.7%)，另外，观察组血压稳定以及尿蛋白降低情况明显优于对照组(P<0.05)，观察组仅有1例患者出现恶心、呕吐症状,明显少于对照组(P<0.05)。观察组血浆黏度有明显的下降,并且明显低于对照组(P<0.05)。结论川芎嗪联合硫酸镁注射液治疗妊娠高血压可稳定血压，缓解恶心呕吐等各种症状。

关键词：妊娠高血压；川芎嗪注射液；硫酸镁

DOI::10.13463/j.cnki.jlzyy.2015.06.019

中图分类号：R714.246文献标志码： A

文章编号：1003-5699(2015)06-0593-03

基金项目:唐山市科技局项目:妊娠高血压综合干预的临床应用(13130277b)。

作者简介:孙君侠(1976-)，女，大学本科，主管护师，主要从事妊娠高血压中西医结合治疗的研究。

收稿日期:(责任编辑：王丹2014-09-21)

Tetromethylpyrazine combined with magnesium sulfate in treatment of hypertension during pregnancy

SUN Junxia,LI Jianfen,YIN Jinli,ZHUO Huifang,WANG Na,GAO Hui,BI Shujie

(Department of Obstetrics and Gynecology,Tangshan Union Medical College Hospital,Tangshan 063000,Hebei Province,China)

Abstract:ObjectiveTo explore the efficacy of traditional Chinese medicine Tetromethylpyrazine combined with magnesium in the treatment of hypertension during pregnancy,provide the basis for the clinical treatment of hypertension in pregnancy.MethodsSelected 90 cases of pregnancy induced hypertension in patients treated in our hospital between September 2010 and December 2013.The 90 patients were divided into a control group and observation group depending on the method of treatment,and 45 patients in each group.Observation group were treated with traditional Chinese medicine Chuan Qiong piperazine combined with magnesium sulfate injection in the treatment,and control group patients using magnesium sulfate injection therapy alone.Observe the clinical effect of the treatment and the two groups of patients’ efficient and plasma viscosity before and after treatment.ResultsThe results showed that patients in the observation group total efficiency (97.8%) was significantly higher than patients in control group (86.7%),in addition,the observation group were stable blood pressure and protein in urine was significantly better than the control group in patients with conditions (P<0.05),observed group only had 1 patient with nausea,vomiting,significantly less than the control patients (P<0.05).Plasma viscosity observed group of patients decreased significantly,and significantly lower than the control patients (P<0.05).ConclusionApplication Tetromethylpyrazine combined with magnesium sulfate injection in the treatment of pregnancy induced hypertension to good effect can stable blood pressure and reduce nausea,vomiting etc.

Keywords:Tetromethylpyrazine;magnesium;gestational hypertension

妊娠期高血压是妊娠期妇女常见的并发症，多发生于妊娠20周之后，临床表现为高血压、蛋白尿、水肿等体征，并易造成多脏器功能障碍[1]，研究发现[2]，我国妊娠期高血压的发病率在7%左右，在孕产妇死亡的原因中占据较大的比例，严重影响着妊娠妇女的生命安全。因此，对于妊娠期高血压，及早进行有效的治疗对降低孕产妇死亡率十分重要[3]。目前，临床上治疗妊娠高血压多采用硫酸镁注射液,然而，由于硫酸镁的有效浓度与中毒浓度相差较小，加之易造成孕妇头痛等并发症，以至于单纯的硫酸镁注射剂治疗效果不佳[4]。……