邓辉+马春清+祝存海



【摘要】目的:探讨经尿道等离子双极电切除术治疗良性前列腺增生对患者尿道功能和性功能的影响。方法:选择122例良性前列腺增生患者为研究对象,随机分为观察组和对照组各61例,观察组采用经尿道双极等离子电切术(PKRP),对照组采用经尿道前列腺电切术(TURP),比较两组手术指标、尿道功能、血红蛋白与红细胞压积、性功能等指标。结果:两组患者在年龄、病史、前列腺体积、IPSS评分、QOL评分、术前血红蛋白水平等一般资料方面无明显统计学差异,具有可比性。(1)手术指标:观察组术中出血量、置管时间、术后住院时间均明显低于对照组[(63.12±7.45 vs. 118.75±13.24)mL、 (3.98±1.12 vs. 5.76±1.65)d、 (5.65±1.22 vs. 7.16±1.68)d](P<0.05、0.01);(2)尿道功能:观察组Qmax明显高于对照组(14.68±2.14 vs. 13.42±2.06)mL/s,RU、IPSS、QOL均明显低于对照组[(18.35±3.24 vs. 24.32±3.54)mL、 (7.68±1.25 vs. 10.12±1.32)分、 (1.82±0.54 vs. 2.12±0.62)分](P<0.05);(3)血红蛋白与红细胞压积:观察组血红蛋白、红细胞压积下降值均明显低于对照组[(11.12±2.18 vs. 16.56±2.34)g/L、 (3.08±0.58 vs. 4.95±1.02)%](P<0.01);(4)性功能:观察组IIEF-5评分明显高于对照组[(23.45±3.24 vs. 21.32±3.12)]分(P<0.05),阴茎勃起障碍、逆行射精发生率均明显低于对照组[(1.64% vs. 9.84%、 32.79% vs. 47.54%)](P<0.05)。结论:经尿道等离子双极电切术具有手术创伤小、恢复快的优点,有利于改善患者尿道功能,对机体功能影响较小。
【关键词】良性前列腺增生;等离子双极电切除术;尿道功能;性功能
Impact of transurethral plasmakinetic resection of prostate on urethral function and sexual function in patients with benign prostatic hyperplasiaDENG Hui, MA Chunqing△, ZHU Cunhai. Department of Urology, Xiaogan Central Hospital, Xiaogan 432000, Hubei, China
【Abstract】Objectives: To study the effect of transurethral plasmakinetic resection of prostate (TPRP) on urethral function and sexual function in patients with benign prostatic hyperplasia. Methods: 122 patients with benign prostatic hyperplasia were divided into observation group and control group. The observation group was given TPRP, while the control group was given transurethral resection of prostate (TURP).The operation index, urethra function, hemoglobin, red blood cells deposited and sexual function of the two groups were compared. Results: There was no statistically significant differences in the postoperative decline of hemoglobin levels, postoperative hospital stay, and quality of life score (QOL), operation time, International Prostate Symptom Score (IPSS) and other aspects between the two groups. (1) Operation: intraoperative blood loss, catheter time, postoperative hospital stay of observation group were significantly lower than these in control group [(63.12±7.45 vs 118.75±13.24)ml, (3.98±1.12 vs 5.76±1.65, 5.65±1.22 vs 7.16±1.68)d (P<0.05, 0.01); (2)Urethra function: Qmax of observation group was significantly higher than that of control group (14.68±2.14 vs 13.42±2.06)ml/s, and RU, IPSS, QOL were significantly lower than these in control group [(18.35±3.24 vs 24.32±3.54)ml, (7.68±1.25 vs 10.12±1.32, 1.82±0.54 vs 2.12±0.62)] (P<0.05). (3) Hemoglobin and red blood cells deposited: hemoglobin, red blood cells decline value of observation group were significantly lower than these in control group [(11.12±2.18 vs 16.56±2.34)g/L, (3.08±0.58 vs 4.95±1.02)%] (P<0.01); (4)Sexual function: IIEF - 5 score of observation group was significantly higher than that of control group (23.45±3.24 vs 21.32±3.12) (P<0.05), penile erectile dysfunction, retrograde ejaculation were significantly lower than these in control group (1.64% vs 9.84%, 32.79% vs 47.54%) (P<0.05). Conclusion: Transurethral plasmakinetic resection of prostate has the advantages of small surgical trauma, rapid recovery and it can improve the function of urinary tract, with less effect on the body function.endprint
【Key words】Benign prostatic hyperplasia; Transurethral plasmakinetic resection of prostate; Urethral function; Sexual function
【中图分类号】R697+.3【文献标志码】A
前列腺增生(benign prostate hyperplasia,BPH)是老年男性中常见泌尿系统疾病,及时解除膀胱流出道梗阻是治疗良性前列腺增生的关键。经尿道前列腺切除术(Transurethral Resection of Prostate, TURP)一直被视为治疗前列腺良性增生的“金标准”,但术中易引发出血、包膜穿孔、术中电切症(TURS)、性功能障碍以及二次手术[1]。经尿道双极等离子电切术(Transurethral plasma kinetic resection of prostate, PKRP)通过高频电流激发生理盐水介质形成动态等离子,作用于靶组织产生电化切割与电凝效果,可有效减少TURP手术并发症[2]的发生。本文采取随机对照研究的方法,探讨TPRP术对良性前列腺增生患者尿道功能与性功能的影响。
1资料与方法
1.1一般资料
选择我院泌尿外科2012年12月至2014年1月收治的122例良性前列腺增生患者为研究对象,年龄61~85岁,平均年龄(57.30±5.65)岁;根据Rous标准判定:前列腺肿大Ⅰ度43例,Ⅱ度45例,Ⅲ度34例;……