经尿道选择性绿激光前列腺汽化术治疗高龄高危良性前列腺增生的临床研究

2016-11-09 06:27:13彭克学谌珩李娓韩愈
中国性科学 2016年4期
关键词:疗效手术

彭克学+谌珩+李娓+韩愈

【摘要】目的:观察经尿道选择性绿激光前列腺汽化术(greenlight photoselective vaporization of prostate,PVP)与经尿道前列腺电切术(TURP)治疗高龄高危良性前列腺增生(benign prostatic hyperplasia,BPH)的临床疗效及安全性分析。方法:临床纳入高龄高危BPH患者90例,根据手术方案的不同分为研究组与对照组,研究组进行PVP,对照组进行TURP。观察两组患者术前、术后1个月、术后12个月最大尿流率(Qmax)、残余尿量(PVR)以及国际前列腺症状评分(IPSS)等,对比两组患者术后并发症的发生率。结果:术前及术后1个月,两组患者Qmax、PVR、IPSS差异均无显著性(P>0.05);术后12个月,研究组Qmax、PVR、IPSS分别为(19.79±5.07)mL/s、(12.69±15.58)mL、(4.92±2.17)分,对照组Qmax、PVR、IPSS分别为(17.98±4.52)mL/s、(23.54±26.66)mL、(7.47±2.02)分,差异均有显著性(P<0.05);研究组术后低钠血症发生率与输血发生率分别为6.67%、2.22%,对照组术后低钠血症发生率与输血发生率分别为22.22%、13.33%,差异均有显著性(P<0.05)。结论:PVP治疗高龄高危BPH的中期疗效优于TURP,能够有效改善患者的排尿,且术后并发症发生率较低,值得推广。

【关键词】经尿道选择性绿激光前列腺汽化术;经尿道前列腺电切术;良性前列腺增生

Clinical research of pvp on the treatment of elderly high-risk benign prostatic hyperplasiaPENG Kexue, CHEN Heng, LI Wei, HAN Yu. Urology Department, Hubei Province Rongjun Hospital, Wuhan 430079, Hubei, China

【Abstract】Objectives: To observe and analyze the clinical effects of greenlight photoselective vaporization of the prostate (PVP) and transurethral resection of the prostate (TURP) on the treatment of elderly high-risk benign prostatic hyperplasia (BPH). Methods: 90 patients with elderly high-risk BPH were selected and divided into research group and control group based on different operation methods. The research group was given PVP, while the control group was given TURP. The Qmax, PVR, and IPSS of patients in both groups before operation, and 1 month, and 12 months after operation were observed. In addition, postoperative complication rates of both groups were observed. Results: Before operation and 1 month after operation, the Qmax, PVR, and IPSS of patients in both groups showed no significant difference (P> 0.05);12 months after operation, the Qmax, PVR, and IPSS of the research group were respectively (19.79±5.07 ml/s, (12.69±15.58) ml, and (4.92±2.17) points, while for the control group respectively (17.98±4.52 ml/s, (23.54±26.66) ml, and (7.47±2.02) points. The differences were significant (P< 0.05); The postoperative hyponatremia and blood transfusion rate of the research group were 6.67% and 2.22%, while 22.22% and 13.33% for the control group. The differences were significant (P< 0.05). Conclusion: The mid-term effect of PVP is better than TURP on the treatment of elderly high-risk BPH. It can effectively improve patients urine with lower postoperative complication rate, which is worth promotion.

【Key words】Greenlight photoselective vaporization of prostate (PVP); Transurethral resection of the prostate (TURP); Benign prostatic hyperplasiaendprint

【中图分类号】R697+.3【文献标志码】A

良性前列腺增生(benign prostatic hyperplasia,BPH)属于临床常见的一种以膀胱出口梗阻为主要表现的疾病[1]。研究表明,BPH的发病率随着年龄的增加出现显著升高的趋势。在70岁以上的老年患者中,尤其是合并重要器官疾病时,被临床称为高龄高危BPH[2,3]。手术是目前临床上治疗BPH较为有效的一种方式,并得到了广泛的开展[4]。目前,临床上用于治疗BPH的手术方案较多,常见的有经尿道钬激光前列腺剜除术(HoLEP)、经尿道前列腺电切术(TURP)[5],近年来,PVP在临床上逐渐开展应用。笔者采用PVP治疗高龄高危BPH,取得了较好的临床疗效,现报告如下。

1资料和方法

1.1一般资料

本文纳入90例我院2010年1月至2014年1月期间收治的高龄高危BPH手术患者作为研究对象,所有患者均同意手术治疗。根据手术方式将患者分为两组各45例。研究……

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