介入方法治疗甲状腺囊性结节对甲状腺功能影响的对比研究

苏淇琛+孙祯

[摘要] 目的 探讨研究应用不同种介入的方法治疗甲状腺囊性结节后对甲状腺功能的影响。方法 随机选择对2015年11月—2016年11月来该院就诊并确诊为甲状腺囊性结节的150例患者，分为观察组与治疗组，每组75例。对观察组患者行经皮32P胶体囊内注射治疗；给予治疗组患者经皮无水乙醇囊内注射治疗，观察对比两组的治疗效果及行介入治疗前后患者的甲功五项（TSH、TT3、TT4、FT3、FT4）的水平值的变化。结果 观察组的总有效率（90.67%）明显高于治疗组的（70.67%），二者差异有统计学意义（P<0.05）；甲功五项检查结果中，以TSH的值为例：观察组治疗前TSH的值为（2.01±2.22）μIU/mL低于治疗后；治疗组治疗前TSH的测量值为（2.24±2.25）μIU/mL高于治疗后值。两组治疗前后组间及组内比较，甲功五项水平差异无统计学意义（P>0.05）。结论 经皮介入治疗甲状腺囊性结节对甲状腺的功能无明显的影响，经皮32P胶体囊内注射的治疗效果高于经皮无水乙醇囊内注射治疗。

[关键词] 介入治疗；甲状腺囊性结节；甲状腺功能

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2017）05（c）-0084-03

[Abstract] Objective To study the effect of different interventional methods in treatment of cystic thyroid nodules on the thyroid function. Methods 150 cases of patients with cystic thyroid nodules diagnosed in our hospital from November 2015 to November 2016 were selected and divided into two groups with 75 cases in each， the observation group were treated with percutaneous 32P colloid injection， and the treatment group were treated with percutaneous ethanol injection， and the treatment effect and level values of TSH， TT3， TT4， FT3， FT4 of patients before and after treatment were observed and compared. Results The total effective rate in the observation group was obviously higher than that in the treatment group， （90.67% vs 70.67%）， and the differences were statistically significant（P<0.05）， and the TSH value in the observation group before treatment was（2.01±2.22）μIU/mL， which was lower than that after treatment， in the treatment group， the TSH measurement value before treatment was（2.24±2.25）μIU/mL， which was higher than that after treatment， and the differences in the five item levels between the two groups were not statistically significant（P>0.05）. Conclusion The percutaneous intervention for cystic thyroid nodules has no obvious effect on the thyroid function， and the treatment effect of percutaneous 32P colloid injection is higher than that of percutaneous ethanol injection.

[Key words] Interventional treatment； Cystic thyroid nodules； Thyroid function

隨着社会、生活的水平不断提高，医疗、科技的逐渐进步，甲状腺相关疾病的发病率以及检查率也在不断提升，该疾病超声引导下的介入治疗方法有其相应的优势[1-2]。该文主要目的是研究对比应用不同种介入的方法治疗甲状腺囊性结节后对甲状腺功能的影响。对2015年11月—2016年11月来该院就诊并确诊为甲状腺囊性结节的150例患者进行分组研究，现报道如下。

1 资料与方法

1.1 一般资料

随机选择对来该院就诊并确诊为甲状腺囊性结节的150例患者，分为观察组与治疗组，每组75例。观察组中，男23例，女52例，年龄在25～68岁之间，年龄均值为（49±6）岁；治疗组中男32例，女43例，年龄在23～65岁之间，均值（48±5）岁。两组所有患者的性别、年龄等一般资料差异无统计学意义（P>0.05）。……