吲哚美辛巴布膏治疗急性踝关节扭伤的临床效果观察

潘永雄　杨广钢　孙占东

[摘要]目的 探讨吲哚美辛巴布膏治疗急性踝关节扭伤的临床效果。方法 选取2015年3月～2016年3月我院收治的120例急性踝关节扭伤患者，随机分为治疗组（61例）和对照组（59例）。治疗组采用吲哚美辛巴布膏外敷；对照组采用扶他林乳胶剂局部适量外用。疗效指标采用Kofoed踝关节评分及VAS视觉模拟评分，观察并比较两组的临床疗效，同时观察药物不良事件。结果 治疗组治疗后第1、5、10天的Kofoed评分均明显高于对照组，差异有统计学意义（P<0.05）。治疗组治疗后第1、5、10天的VAS评分均明显低于对照组，差异有统计学意义（P<0.05）。治疗组的临床疗效优于对照组，差异有统计学意义（P<0.05）。两组均未见不良反应发生。结论 吲哚美辛巴布膏治疗急性踝关节扭伤的效果明显优于扶他林乳胶剂局部外用，值得临床推广应用。

[关键词]吲哚美辛巴布膏；急性踝关节扭伤；临床疗效

[中图分类号] R684.7 [文献标识码] A [文章编号] 1674-4721（2017）06（a）-0095-03

[Abstract]Objective To investigate the clinical effect of Indometacin Cataplasms in treating acute ankle sprain.Methods From March 2015 to March 2016，120 patients with acute ankle sprain in our hospital were selected and randomly divided into the treatment group （61 cases） and the control group （59 cases）.The treatment group was treated with Indometacin Cataplasms，the control group was treated with Voltaren Gel.The Kofoed ankle joint scales and the VAS scores were utilized，the clinical effects between the two groups was observed and compared.The adverse effect of drug were also recorded in the whole process.Results The Kofoed score of the treatment group on the first，fifth，tenth day after treatment was significantly higher than that of the control group，with significant difference （P<0.05）.The VAS score of the treatment group on the first，fifth，tenth day after treatment was significantly lower than that of the control group，with significant difference （P<0.05）.The clinical efficacy of the treatment group was better than that of the control group，with significant difference （P<0.05）.Ther was no adverse reactions occurred in the two groups.Conclusion The effect of Indometacin Cataplasms in the treatment of acute ankle sprain is superior to topical Votalin Gel，it is worthy of clinical promotion and application.

[Key words]Indometacin Cataplasms；Acute ankle sprain；Clinical effect

踝关节扭伤是最常见运动损伤，临床表现包括伤后迅速出现扭伤部位的疼痛和肿胀，随后出现皮肤淤斑，严重者患足因为疼痛肿胀而不能活动。本病治疗不当可导致慢性踝关节不稳，日后容易出现踝关节反复扭伤的情况，后期发展为创伤性关节炎等并发症[1-2]。急性踝关节扭伤治疗目标是尽量、尽快地减轻疼痛，消除肿胀及控制局部炎癥，使踝关节损伤的韧带可以及早地恢复，预防后期慢性踝关节不稳的出现[3]。临床上对急性踝关节扭伤的治疗手段极多，在休息、冷敷、加压与抬高患肢（rest、ice、compression and elevation，RICE）的基础上[4]，早期治疗包括中医治疗、手术治疗等多种方式[5]。为观察吲哚美辛巴布膏的临床疗效，本研究采用吲哚美辛巴布膏与临床常用的扶他林乳胶剂治疗急性踝关节扭伤，并对其疗效进行对比，现报道如下。

1资料与方法

1.1一般资料

本研究按照前瞻性、随机、单盲临床对照设计。……