布文博 张珂 张倩


[摘要]目的:探讨机械磨削术治疗Riehls黑变病的临床疗效。方法:2010年2月-2018年10月笔者科室收治瑞尔黑变病患者8例,所有患者采用机械磨削治疗,均随访1年以上。利用5分法对机械磨削治疗的临床疗效进行评价,患者对治疗满意度进行评价。结果:8例Riehls黑变病患者,经治疗皮损均较治疗前消退75%以上,未见复发,7例非常满意,1例满意。不良反应均能耐受,主要为红斑、结痂及短暂的色素沉着。结论:机械磨削术治疗Riehls黑变病安全、有效。
[关键词]Riehls黑变病;皮肤磨削术;机械磨削;临床疗效;色素沉着
Abstract: Objective To evaluate the clinical efficacy of mechanical dermabrasion in the treatment of Riehls melanosis. Methods From February 2010 to October 2018, 8 patients with Riehls melanosis were treated with conventional mechanical dermabrasion in our hospital, followed up for at least one year. The clinical efficacy was evaluated by the physicians based on the 5-point scale. Satisfaction scores was evaluated by the patients. Results There were 8 patients in this group. After treatment, all the patients had more than 75% improvement. None of the patients got recurrence. All the patients rated their results as satisfied or very satisfied. Adverse reactions were mild, including erythema, scab and transient pigmentation. Conclusion Mechanical dermabrasion is safe and effective in the treatment of Riehls melanosis.
Key words: Riehls melanosis; dermabrasion; mechanical dermabrasion; clinical effect; pigmentation
Riehls黑变病被认为是接触性皮炎的一种表现形式,本病多见于中年女性患者,多在冬季发病,有较长潜伏期,病程进展缓慢。患者多有明显的职业接触史,皮疹易发生在暴露部位,如面颈部。发病前轻度瘙痒,皮肤出现水肿性红斑,反复发作后可发生弥漫性或网状色素沉着斑,呈淡褐色至深褐色,同时部分伴有毛细血管扩张,痤疮样损害,黑色苔藓样毛囊性小丘疹,轻度皮肤萎缩。部分患者可伴有头痛、头晕、疲乏无力、食欲不振等全身症状。临床治疗相对棘手,常采用治疗方法包括药物、激光、机械磨削等。
1 资料和方法
1.1 一般资料:选择2010年2月-2018年10月在笔者科室进行机械磨削治疗的8例Riehls黑变病患者作为研究对象。所有患者均为女性,均有激光和口服外用药物治疗史;平均年龄33.87±8.44(21~49)岁,平均病程13.25±6.20(7~23)个月;其中3例面颈部均累及,5例仅累及面部。所有患者均经临床或病理确诊为Riehls 黑变病,无严重内科疾病,无明显手术禁忌证。……