吲哚布芬联合补阳还五汤治疗气滞血瘀型脑梗死的临床效果

晏淑川 胡淑云

[摘要]目的 探討吲哚布芬联合补阳还五汤治疗气滞血瘀型脑梗死的临床效果。方法 选取2019年1～10月我院收治的110例气滞血瘀型脑梗死患者为研究对象，按照随机数字表法将其分为对照组（55例）和观察组（55例），对照组患者运用常规治疗方法，观察组患者在常规治疗方法的基础上运用吲哚布芬联合补阳还五汤，通过比较两组患者治疗前后的中医证候积分、Barthel评分、中医疗效、神经功能缺损疗效，判定临床效果。结果 治疗前，两组患者的中医证候积分比较，差异无统计学意义（P>0.05）;治疗后，两组患者的中医证候积分均低于治疗前，且观察组患者的中医证候积分低于对照组，差异有统计学意义（P<0.05）。治疗前，两组患者的Barthel评分比较，差异无统计学意义（P>0.05）;治疗后，两组患者的Barthel评分均高于治疗前，且观察组高于对照组，差异有统计学意义（P<0.05）。观察组患者的中医疗效总有效率为96.36%，高于对照组的83.64%，差异有统计学意义（P<0.05）;神经功能缺损疗效比较，观察组患者的总有效率为92.73%，高于对照组的70.91%，差异有统计学意义（P<0.05）。结论 吲哚布芬联合补阳还五汤治疗气滞血瘀型脑梗死有助于提高临床效果。

[关键词]吲哚布芬;补阳还五汤;气滞血瘀型脑梗死;脑卒中;临床效果

[中图分类号] R743.3          [文献标识码] A          [文章编号] 1674-4721（2020）7（a）-0176-04

Effect of Indobufen combined with Buyang Huanwu Decoction treating Qi-stagnation and blood-stasis type of cerebral infarction

YAN Shu-chuan   HU Shu-yun

Department of Internal Medicine， Hospital of Traditional Chinese Medicine of Yichun City in Jiangxi Province， Yichun 336000， China

[Abstract] Objecctive To investigate the clinical effect of Indobufen combined with Buyang Huanwu Decoction treating qi-stagnation and blood-stasis type of cerebral infarction. Methods From January to October 2019， 110 patients with cerebral infarction of qi-stagnation and blood-stasis type admitted to our hospital were selected as research objects. They were divided into control group （55 cases） and observation group （55 cases） according to random number table method. The control group used conventional treatment methods. The observation group used Indobufen combined with Buyang Huanwu Decoction on the basis of conventional treatment methods. The clinical effects were determined by comparing the traditional Chinese medicine （TCM） syndrome score， Barthel score， TCM curative effect and neurological function defect curative effect of the two groups of patients before and after treatment. Results There were no significant differences in TCM syndrome scores between the two groups before treatment （P>0.05）. After treatment， the TCM syndrome scores of the two groups were lower than those before treatment， and the observation group was lower than the control group， the differences were statistically significant （P<0.05）. There were no significant differences in Barthel scores between the two groups before treatment （P>0.05）. After treatment， the Barthel scores of the two groups were higher than those before treatment， and the observation group was higher than the control group， the differences were statistically significant （P<0.05）. The total effective rate of patients of efficacy of TCM in the observation group was 96.36%， which was higher than 83.64% in the control group， the difference was statistically significant （P<0.05）. In comparing neurological function defect curative effect， the total effective rate of the observation group was 92.73%， higher than that of the control group of 70.91%， and the difference was statistically significant （P<0.05）. Conclusion Indobufen combined with Buyang Huanwu Decoction treating qi-stagnation and blood-stasis type of cerebral infarction is helpful to increase the clinical effect.

[Key words] Indobufen; Buyang Huanwu Decoction; Qi-stagnation and blood-stasis type of cerebral infarction; Stroke; Clinical efficacy

脑梗死，又称为缺血性脑卒中，其病因主要是由各种原因致颅内及大动脉粥样硬化，导致血小板的黏附、聚集及释放，形成血栓，致管腔闭塞、堵塞血管，引起病变血管血流减少，导致低灌注等病变。针对这种病变，在脑卒中的临床诊疗规范中均采用抗血小板聚集治疗，最常用的药物就是阿司匹林。但服用阿司匹林时，常会出现出血及胃肠道反应的缺血性心脑血管病变或血栓栓塞疾病事件[1]。吲哚布芬是一丁异二氢氮茚基苯基一丁酸衍生物，属非类固醇类抗血小板药物，是一种新型的抗血小板药物。有研……