氯吡格雷联合阿司匹林肠溶片治疗急性心肌梗塞疗效观察

【摘  要】目的：探究在治疗急性心肌梗塞疾病时，采用氯吡格雷、阿司匹林肠溶片的临床效果。方法：选取在我院进行治疗的急性心肌梗塞患者作为研究对象。参选患者均经过临床诊断，选取患者例数为96例，选取时间在2016年4月-2019年4月结束。将本次参选的患者进行分组对比，分组方式采用的是抽签法。本次分为对照组和实验组，每组有患者人数为48例。对照组采用的是阿司匹林肠溶片，实验组在对照组的基础上增加氯吡格雷，对实验组、对照组患者的临床效果进行对比。结果：实验组患者的治疗有效率为95.83%，与对照组患者的81.25%相比，实验组更具有优势，实验组、对照组数据对比经过统计学计算有差异存在，统计学意义存在（P<0.05）;实验组患者的不良反应发生率远低于对照组，组间差异存在临床对比意义（P<0.05）。结论：采用氯吡格雷与阿司匹林联合治疗急性心肌梗塞有显著效果，值得在临床中推广应用。

【关键词】急性心肌梗塞;阿司匹林肠溶片;氯吡格雷;疗效

【中图分类号】R542      【文献标识码】A      【文章编号】1672-3783（2020）06-0048-02

【Abstract】Objective： To explore the clinical effects of clopidogrel and aspirin enteric-coated tablets in the treatment of acute myocardial infarction.Methods： The patients with acute myocardial infarction treated in our hospital were selected as the research subjects. All the candidates were clinically diagnosed， and the number of selected patients was 96， and the selection time ended from April 2016 to April 2019. This election of patients were compared in groups， the grouping method is drawn. This time divided into control group and experimental group， each group has 48 patients. Aspirin enteric-coated tablets were used in the control group and clopidogrel was added to the control group The clinical effects of the experimental group and the control group were compared. Results： the effective rate of treatment in the experimental group was 95.83%， compared with 81.25% in the control group， the experimental group had more advantages， and the data comparison between the experimental group and the control group was statistically different and statistically significant （P<0.05）. Conclusion： The combination of clopidogrel and aspirin in the treatment of acute myocardial infarction has remarkable effect and is worth popularizing in clinic.

【Key words】Acute myocardial infarction; Aspirin enteric-coated tablets; Clopidogrel; Efficacy

近年來我国心脑血管疾病的发病率呈逐年上升趋势，在心脑血管疾病中比较常见的一种疾病为急性心肌梗塞。患者患有急性心肌梗塞后会对患者的生活带来严重的影响，同时对于患者的生命安全也会造成严重的威胁[1-2]。目前对于急性心肌梗塞的治疗主要通过药物治疗的方式，临床常用药物种类繁多，其中常见的为阿司匹林肠溶片和氯吡格雷。据临床研究结果显示，单一用药的临床效果差于联合用药的临床效果。为此，本次选取在我院进行治疗的患者作为研究对象，分析联合用药的临床价值，具体详情如下。

1. 资料与方法

1.1患者资料