丁苯酞注射液联合通脑饮治疗急性脑梗死患者的效果

付丽洁

【摘要】 目的：探讨急性脑梗死（ACI）患者丁苯酞注射液联合通脑饮治疗的效果及对脑血流动力学的影响。方法：选取本院在2019年1月-2020年6月确诊并治疗的184例ACI患者，依据不同的治疗方式将患者分为两组，每组92例。两组均接受常规治疗，对照组联合应用丁苯酞注射液，研究组在对照组基础上联合使用通脑饮。观察并比较两组治疗前后ADL评分、脑血流动力学指标及疗效。结果：研究组治疗14、30 d后ADL评分均高于对照组（P<0.05）。研究组总有效率高于对照组（P<0.05）。研究组治疗后Vs、Vm均高于对照组，PI低于对照组，差异均有统计学意义（P<0.05）。结论：ACI患者在临床治疗过程中联合使用丁苯酞注射液及通脑饮，可显著提高治疗效果、改善患者的脑血流动力学、提高生活能力。

【关键词】 急性脑梗死 丁苯酞注射液 脑血流动力学 通脑饮

Effect of Butyphthalide Injection Combined with Tongnaoyin in the Treatment of Patients with Acute Cerebral Infarction/FU Lijie. //Medical Innovation of China， 2021， 18（31）： -107

[Abstract] Objective： To investigate the therapeutic effect of Butyphthalide Injection combined with Tongnaoyin in patients with acute cerebral infarction （ACI） and its effect on cerebral hemodynamics. Method： A total of 184 ACI patients diagnosed and treated in our hospital from January 2019 to June 2020， they were divided into two groups according to the treatment method， 92 cases in each group. Both groups received routine treatment， the control group combined with Butyphthalide Injection， the study group used Tongnaoyin on the basis of the control group. ADL scores， cerebral hemodynamic indexes before and after treatment and curative effect were observed and compared between two groups. Result： The ADL scores of the study group at 14 and 30 d after treatment were higher than those of the control group （P<0.05）. The total effective rate of the study group was higher than that of the control group （P<0.05）. After treatment， Vs and Vm of the study group were higher than those of the control group， and PI was lower than the control group， the differences were statistically significant （P<0.05）. Conclusion： ACI patients treated with Butyphthalide Injection combined with Tongnaoyin can significantly improve the effect of treatment， improve patient’s cerebral hemodynamics and living ability.

[Key words] Acute cerebral infarction Butyphthalide Injection Cerebral hemodynamics Tongnaoyin

First-author’s address： Xincheng Hospital， Liaoyang Central Hospital， Liaoyang 111000， China

doi：10.3969/j.issn.1674-4985.2021.31.025

腦血管病是临床中一种常见的神经系统疾病，逐渐成为我国农村及城市人口中的首位致死及致残原因[1]。近几年以来共在临床中的发病率逐年升高，且发病年龄也表现出持续降低，增加了患者家庭及社会的负担[2]。急性脑梗死（ACI）是临床中较为常见的一种神经系统脑血管疾病类型，导致ACI的诱因复杂多样，而各种因素之间互相影响、作用，导致脑部血液的正常循环及供应受到阻碍，发生缺氧、缺血，使得脑组织进一步坏死，机体出现相关的神经功能缺损表现[3]。在所有的ACI患者中，缺血性占比最高，为70%～80%。尤其在发病急性期内，中心坏死区域及周围缺血半暗带共同构成了病灶。……