玉屏风散联合疫苗对慢性阻塞性肺疾病缓解期患者肺功能及气道炎性因子的影响

梁金池

摘要：目的 探讨对慢性阻塞性肺疾病（COPD）缓解期的患者，采取玉屏风散、疫苗的联合方案对患者肺功能、炎性因子指标的影响。方法 纳入80例研究对象并随机分成治疗组与对照组各40例，对照组使用止咳化痰、氧疗及疫苗注射，治疗组在对照组的基础上加用玉屏风散治疗，对2组经30d的治疗效果、肺功能與炎性因子指标变化进行观察对比。结果 治疗组总有效率92.50%，比对照组75.00%更高（P<0.05）;治疗后2组第一秒用力呼气容积（FEV1）、用力肺活量（FVC）、FEV1/FVC水平均较治疗前提高（P<0.05），且治疗组提高程度显著优于对照组（P<0.05）;治疗后2组C反应蛋白（CRP）、降钙素原（PCT）水平较治疗前降低（P<0.05），且治疗组降低程度显著优于对照组（P<0.05）。结论 对COPD缓解期的患者采取玉屏风散联合疫苗注射的效果满意，显著改善患者肺功能及降低炎性因子水平，值得推广。

关键词：玉屏风散;疫苗;慢性阻塞性肺疾病;缓解期;肺功能;气道炎性因子

中图分类号：R563.3 文献标志码：B 文章编号：1007-2349（2021）04-0048-04

Effect of Yupingfeng Powder Combined Vaccine on Pulmonary Functionand Airway Inflammatory Factors in Patients with ChronicObstructive Pulmonary Disease in Remission

LIANG Jin-chi

（Traditional Chinese Medicine Hospital of Kaiping City， Kaiping 529300， China）

【Abstract】Objective： To study the effect of the combination of Yupingfeng Powder and vaccine on the lung function and inflammatory factors in patients with chronic obstructive pulmonary disease （COPD） in remission period. Methods： 80 study subjects were enrolled and randomly divided into a treatment group and a control group， 40 cases per group. The control group was given medicine for relieving cough and reducing sputum， oxygen therapy and vaccine injection and the treatment group was added Yupingfeng Powder on the basis of the control group. The curative effect， lung function and inflammatory factor index changes of the two groups were observed and compared after 30-day treatment. Results： The total effective rate of the treatment group was 92.50%， which was higher than 75.00% of the control group （P<0.05）. The forced expiratory volume （FEV1）， forced vital capacity （FVC） and FEV1/FVC levels in the two groups were higher in the first second after treatment. The level of C-reactive protein （CRP） and procalcitonin （PCT） in the two groups after treatment increased （P<0.05）， and the degree of improvement in the treatment group was significantly better than that of the control group （P<0.05）， and the degree of reduction in the treatment group was significantly better than that in the control group （P<0.05）. Conclusion： The effect of Yupingfeng Powder combined vaccine injection is satisfactory for COPD patients in remission， which significantly improves the lung function of patients and reduces the level of inflammatory factors， and is worthy of application.

【Key words】Yupingfeng Powder; Vaccine; Chronic obstructive pulmonary disease; Remission; Lung function; Airway inflammatory factors

慢性阻塞性肺疾病（Chronic obstructive pulmonary disease，COPD）有着越来越高的疾病发病率，这与目前空气环境以及吸烟人群的增加有着密不可分的联系[1]。COPD缓解期是指急性发作期的患者经治疗好转进到缓解期，然而病情却仍旧持续进展，肺功能也持续恶化，缓解期仍旧存在不同程度的咳嗽。咳痰及胸闷等症状，需反复的住院治疗，这给患者身心带来极大痛苦，因此需要应用有效的方法治疗。西医针对COPD缓解期的预防急性发作目前常是采取常规止咳化痰、解痉平喘及疫苗注射方式，但疗效欠佳，临床中为了进一步的控制患者的病情，多提倡应用中西医结合治疗的方法[2]。祖国医学认为COPD主要因感受外邪，而玉屏风散本着标本兼治的原则，能起到固表不留邪、御风邪及祛邪扶正的效果[3]。本次研究中，纳入了80例COPD缓解期患者，探讨了使用玉屏风散联合疫苗对患者肺功能、气道炎性因子水平的影响，现报道如下。……