李元明 白丽杉


【摘要】目的:浅析泮托拉唑在治疗消化性溃疡合并 PUCHC(上消化道出血)的效果评价。方法:此次研究对象均来源于 2019 年 4月 -2020 年 4 月本院收治的消化性溃疡合并上消化道出血患者,前 30 名入院的患者设定为对照组,口服奥美拉唑治疗,后入院的 30 名患者设定为观察组,口服泮托拉唑治疗,比较两组患者治疗效果和不良反应发生率。结果:观察组治疗效果及不良反应发生率明显优于对照组,经对比统计学意义成立 (P < 0.05)。结论:对消化溃疡合并消化道出血的患者采取泮托拉唑治疗,不但能减少不良反应发生率,还能提升治疗效果,值得应用推广。
【关键词】泮托拉唑;消化性溃疡;上消化道出血
【中图分类号】R573 【文献标识码】A 【DOI】10.12332/j.issn.2095-6525.2021.01.067
【Abstract】Objective:To evaluate the efficacy of pantoprazole in the treatment of peptic ulcer complicated with PUCHC (upper gastrointestinal bleeding). methods:The research objects are derived from April 2019 - April 2020 of peptic ulcer with upper gastrointestinal hemorrhage patients admitted in our hospital, the top 30 set the hospitalized patients as control group, oral omeprazole treatment, 30 patients admitted to hospital after setting as the observation group, oral diazepam tora azole treatment, compared two groups of patients treatment effect and the incidence of adverse reactions. Results:The treatment effect and the incidence of adverse reactions in the observation group were significantly better than those in the control group, with statistical significance (P < 0.05). Conclusion:Pantoprazole treatment for patients with digestive ulcer complicated with gastrointestinal bleeding can not only reduce the incidence of adverse reactions, but also improve the therapeutic effect, which is worthy of application and promotion.
【Key words】Pantoprazole; Peptic ulcer; Upper gastrointestinal hemorrhage
在消化系統疾病当中,消化性溃疡合并上消化道出血是最为常见的病症之一,根据相关调查得知,患有消化性溃疡合并上消化道出血的患者大约占比 25%,针对消化溃疡患者合并消化道出血的患者来说,其存在诸多临床表现,比如低蛋白血症、黑便、呕血等等,并且具备较高的致死率,倘若患者未能及时进行诊治,会严重危及患者的生命安全。当前抑酸药物是临床中最为常见的药物,应用 H2 受体阻滞剂可起到控制胃酸分泌的作用,但该药物不具备良好的耐受性,极有可能会影响到患者的预后效果,而且在临床中不建议广泛应用,对此,部分医院为了快速解决以上问题,不断在消化性溃疡的治疗中应用质子泵抑制剂,并获得了较好的效果,泮托拉唑是质子泵抑制剂的第三代,其不但具备较高的安全性,还能对胃酸分泌起到控制作用 [1-2]。……