大柴胡汤加减方治疗高血压脑出血的前瞻性研究

冯庆琪 王巍 张征达 李昂 于朝春

【摘要】目的：探索针对高血压脑出血疾病有效合理地治疗方式，并将其应用于临床治疗和预后工作中，进而为制定相应的治疗措施提供参考。方法：选取本院脑病科在2019年6月至2020年6月收治的100例高血压脑出血（HICH）患者，随机分为对照组和观察组。对照组给予常规治疗，观察组在常规治疗的基础上给予大柴胡汤加减方治疗。疗程结束后，分别进行血液流变学和全血粘度指标，脑部头颅CT，血压，NIHSS评分和BI评分等检测。结果：研究结果显示，大柴胡汤加减方治疗对高血压脑出血病人具有明显的改善血液循环的效果；观察组在治疗后的颅内血肿的残余量的降低情况更明显；大柴胡汤加减方的治疗使高血压脑出血患者的神经功能缺损程度以及日常生活能力都得到了改善。结论：大柴胡汤加减方在治疗高血压脑出血和预后方面都具有疗效，对血肿吸收具有积极作用。

【关键词】大柴胡汤加减方；高血压脑出血.；临床预后.；临床治疗

【中图分类号】R259 【文献标识码】A 【文章编号】2096-5249（2021）12-0001-03

Prospective study of Dachihu soup and subtraction prescription to treat hypertensive cerebral hemorrhage

Feng Qingqi1，Wang Wei1，Zhang Zhengda1，Li Ang1，Yu Chaochun2△

1.Department of Neurosurgery， Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine， Shanghai 00032，China；

2.Department of Neurosurgery， Shanghai Hospital of Integrated Traditional Chinese and Western Medicine， Shanghai University of Traditional Chinese Medicine， Shanghai 200032，China

【Abstract】Objective：Explore effective and reasonable treatment methods for hypertensive cerebral hemorrhage diseases， and apply them to clinical treatment and prognostic work， thus provide reference for formulating corresponding treatment measures.Methods：A total of 100 patients with hypertensive cerebral hemorrhage （ HICH ） admitted to the Department of Encephalopathy of our hospital from June 2019 to June 2020 were selected and randomLy divided into the control group and the observer group. The control group was given conventional treatment， and the observer group was given modified Dachaihu Decoction on the basis of conventional treatment. After the treatment， hemorheology and whole blood viscosity indexes， brain CT， blood pressure， NIHSS score and BI score were detected.Results：The research results showed that the treatment of Dachaihu soup and subtraction significantly improved blood circulation in patients with hypertensive cerebral hemorrhage， increased the reduction of intracranial hematoma after the treatment， and improved the neurofunction defect and daily life ability of patients with hypertensive cerebral hemorrhage.Conclusion：Dachaihu soup and subtraction in the treatment of hypertensive cerebral hemorrhage and prognosis and positive effect on hematoma absorption.

【Key words】Dachaihu soup plus prescription； hypertensive cerebral hemorrhage； clinical prognosis； clinical treatment

高血壓性脑出血是一种常见现象高血压并发症，它具有突然发作，快速发展和许多不良并发症的特点，它通过将减少脑组织的氧气供应，并对患者的神经功能造成不同程度的损害[1]。随着现代医疗卫生水平的不断提升，高血压脑出血患者术后存活率得到提升，然而常规的治疗尽管能够在一定程度上缓解患者的临床症状，却难以解决脑细胞缺氧、血管源性脑水肿等问题。……