张磊 刘迎迎 于杰 郭伟星 李运伦
摘要 通过梳理中医学关于“痰”“瘀”的古、今文献,厘清“痰瘀互结证”的证治源流,对“痰瘀互生互变,共同致病”的病理机制进行深入探析,提出痰、瘀既是气血津液代谢失司的病理产物,又可以成为新的致病因素,二者同源共生、互生互化、交互同病,全程参与高血压的发生及演变,成为高血压中医病机的关键环节,为中医临床从痰瘀互结辨治高血压提供了理论依据。
关键词 高血压;痰瘀互结证;证治源流;证候本质;痰瘀生化互变;病理机制;关键环节;理论依据
Abstract By analyzing ancient and modem literature about the phlegm and blood stasis in Traditional Chinese Medicine(TCM),this paper clarified the origin and essence of the diagnosis and treatment of “syndrome of intermingled phlegm and blood stasis”,and explored and analyzed the pathogenesis of “phlegm and blood stasis promoting each other to cause disease” in depth.It is proposed that phlegm and blood stasis can be both pathological products from the metabolic dysfunction of qi,blood,and fluid,and a new pathogenic factor.These two symptoms are of same origin and promotes each other,whose interaction fully involved in the occurrence and process of hypertension,becoming a key link in the pathogenesis of hypertension,which provides a theoretical basis for treating hypertension from the perspective of intermingled phlegm and blood stasis for TCM clinically.
Keywords Hypertension; Syndrome of intermingled phlegm and blood stasis; Origin and essence of diagnosis and treatment; Essence of syndromes; Phlegm-stasis interaction; Pathological mechanism; Key link; Theory basis
中图分类号:R255.3;R259文献标识码:Adoi:10.3969/j.issn.1673-7202.2021.10.012
高血压是以体循环动脉压增高为主要表现的临床综合征,严重影响心、脑、肾等重要脏器的结构与功能,是我国心脑血管疾病最主要的危险因素和心脑血管死亡的主要原因[1],是目前医学界公认的心脑血管疾病最重要的危险因素,也是全世界范围内威胁人类健康甚至生命的主要疾病之一[2]。目前,现代医学虽然对高血压的发病机制进行了深入探讨,并针对不同的发病机制进行了有针对性的干预,但是在改善临床症状方面仍乏善可陈,而中医药在治疗高血压方面取得了很大的成绩,在保护靶器官,减少及延缓并發症,改善患者症状,提高生命质量方面具有明显优势[3]。因此,如何充分发挥中医药在诊治高血压中的优势是中医从业者面临的一大难题。
通过梳理古今中医学文献,不仅未见有关高血压的系统论述,更未曾……